Evidence map›Paper›PMID 27803884›Full record

ArticleAsia Pacific allergy2016

Imidacloprid inhibits IgE-mediated RBL-2H3 cell degranulation and passive cutaneous anaphylaxis.

Linbo Shi, Li Zou, Jinyan Gao, Huaing Xu, Xiaoyun Shi, Hongbing Chen

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Asia Pacific allergy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Evidence-based complementary and alternative medicine : eCAM · 2019
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Linbo ShiState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Li ZouState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Jinyan GaoSchool of Food Science, Nanchang University, Nanchang 330047, China.
Huaing XuDepartment of Rehabilitation, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Xiaoyun ShiDepartment of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Hongbing ChenState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Nanchang University · CNFirst Affiliated Hospital of Nanchang University · CNState Key Laboratory of Food Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImidacloprid has been commonly used as a pesticide for crop protection and acts as nicotinic acetylcholine receptor agonists. Little information about the relationship between imidacloprid and allergy is available.

objectiveThis study aims to examine the effects of imidacoprid on IgE-mediated mast cell activation.

methodsThe rat basophilic leukemia cell line RBL-2H3 (RBL-2H3 cells) were treated with 10

resultsIt was shown that imidacoprid suppressed the production of histamine, β-hexosaminidase, leukotriene C4, interleukin-6, tumor necrosis factor-α, and Ca

conclusionIt is the first time to show that imidacloprid suppressed the activation of RBL-2H3 cells.

Indexed as

Ca2+ influxImidaclopridMast cells

Identifiers

PMID27803884
PMCPMC5088260
OpenAlexW2543472027

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.