ArticleInternational journal of ophthalmology2016
A Meta-analysis of the association between different genotypes (
Article in International journal of ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Leber's Hereditary Optic Neuropathy with Mitochondrial DNA Mutation G11778A: A Systematic Literature Review and Meta-Analysis.BioMed research international · 2023Pooled it
- Differentiating Leber's Hereditary Optic Neuropathy from Optic Neuritis in a Clinical Setting.Annals of Indian Academy of Neurology · 2025Article
- Leber's hereditary optic neuropathy and multiple sclerosis: overlap between mitochondrial disease and neuroinflammation.Frontiers in neurology · 2025Review
- Therapeutic benefit of idebenone in patients with Leber hereditary optic neuropathy: The LEROS nonrandomized controlled trial.Cell reports. Medicine · 2024Article
- Efficacy of Intravitreal rAAV2-ND4 Injection in Treated Versus Fellow Eyes with Leber's Hereditary Optic Neuropathy: A Meta-Analysis.Neuro-ophthalmology (Aeolus Press) · 2024Review
- The Relative Preservation of the Central Retinal Layers in Leber Hereditary Optic Neuropathy.Journal of clinical medicine · 2022Article
- Natural history of patients with Leber hereditary optic neuropathy-results from the REALITY study.Eye (London, England) · 2022Article
- Leber hereditary optic neuropathy-new insights and old challenges.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Review
- Mitochondrial Dynamics during Development.Newborn (Clarksville, Md.)Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo analyze the influences of different genotypes (
methodsAfter a systematic literature search, all relevant studies evaluating the association between the three primary mutations of LHON and visual prognosis were included. All statistical tests were calculated with Revman 5.2 and STATA 12.0.
resultsTen independent studies were included finally. A significant association between the three primary mutations and prognostic vision over 0.3 were found in
conclusionFrom pairwise comparison, we conclude that these three different genotypes of LHON are related to patients' visual prognosis. The
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Registered trials
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