Evidence map›Paper›PMID 27803762›Full record

ReviewOxidative medicine and cellular longevity2016

Role of Antioxidants and Natural Products in Inflammation.

Palanisamy Arulselvan, Masoumeh Tangestani Fard, Woan Sean Tan, Sivapragasam Gothai, Sharida Fakurazi, Mohd Esa Norhaizan, S Suresh Kumar

2 registry-linked trialsOpen access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 441 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
441citing papers in PubMed, 1 pooled it
78.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05271695 completednot on this mapstarted 2019, after this paper: background citation

Effect of Dietary Inflammatory Index on Inflammatory Markers and Metabolic Parameters, in Patients With Type 2 Diabetes Mellitus

TypeobservationalSponsorIstanbul UniversityRan2019 to 2020Enrolled150ConditionsType 2 Diabetes, Dietary Inflammatory Index (DII), Inflammation, Medical Nutrition Therapy
NCT06006182 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effects of Freeze-Dried Whole Grape Powder on Chronic Disease and Cardiovascular Risk Factors, Hunger, Satiety, and Body Composition in Free-Living People-a Pilot Study

TypeinterventionalSponsorCalifornia State Polytechnic University, PomonaRan2023 to 2024Enrolled30ConditionsHealthy PeopleArmsGrape Powder
3 · Its place in the literature

Who cites it

441 citing papers in PubMed, 1 synthesis or guideline pooled it, 971 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Phytochemical Profile and Biological Activities ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
  8. International journal of molecular sciences · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Zingerone attenuates steatosis via downregulation of AQP9 in hepatocytes.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review

381 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Palanisamy ArulselvanLaboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.ORCID 0000-0002-1835-9738
Masoumeh Tangestani FardDepartment of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Woan Sean TanLaboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Sivapragasam GothaiLaboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Sharida FakuraziLaboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.ORCID 0000-0001-8986-876X
Mohd Esa NorhaizanDepartment of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.ORCID 0000-0003-1545-0306
S Suresh KumarDepartment of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Universiti Putra Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is a comprehensive array of physiological response to a foreign organism, including human pathogens, dust particles, and viruses. Inflammations are mainly divided into acute and chronic inflammation depending on various inflammatory processes and cellular mechanisms. Recent investigations have clarified that inflammation is a major factor for the progression of various chronic diseases/disorders, including diabetes, cancer, cardiovascular diseases, eye disorders, arthritis, obesity, autoimmune diseases, and inflammatory bowel disease. Free radical productions from different biological and environmental sources are due to an imbalance of natural antioxidants which further leads to various inflammatory associated diseases. In this review article, we have outlined the inflammatory process and its cellular mechanisms involved in the progression of various chronic modern human diseases. In addition, we have discussed the role of free radicals-induced tissue damage, antioxidant defence, and molecular mechanisms in chronic inflammatory diseases/disorders. The systematic knowledge regarding the role of inflammation and its associated adverse effects can provide a clear understanding in the development of innovative therapeutic targets from natural sources that are intended for suppression of various chronic inflammations associated diseases.

Indexed as

AnimalsAntioxidantsBiological ProductsChronic DiseaseHumansInflammationSignal TransductionAntioxidantsBiological Products

Identifiers

PMID27803762
PMCPMC5075620
OpenAlexW2530157596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.