Evidence map›Paper›PMID 27803657›Full record

ArticleFrontiers in human neuroscience2016

Pramipexole Increases Go Timeouts but Not No-go Errors in Healthy Volunteers.

Xue Qing Yang, Daniel Glizer, Andrew Vo, Ken N Seergobin, Penny A MacDonald

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Approach to Cognitive Impairment in Parkinson's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020
    Review
  4. The adverse effects of pramipexole on probability discounting are not reversed by acute DEuropean neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2020
    Article
  5. Article
  6. Dopamine effects on frontal cortical blood flow and motor inhibition in Parkinson's disease.Cortex; a journal devoted to the study of the nervous system and behavior · 2019
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xue Qing YangMacDonald Lab, Brain and Mind Institute, University of Western Ontario London, ON, Canada.
Daniel GlizerMacDonald Lab, Brain and Mind Institute, University of Western Ontario London, ON, Canada.
Andrew VoMacDonald Lab, Brain and Mind Institute, University of Western Ontario London, ON, Canada.
Ken N SeergobinMacDonald Lab, Brain and Mind Institute, University of Western Ontario London, ON, Canada.
Penny A MacDonaldMacDonald Lab, Brain and Mind Institute, University of Western OntarioLondon, ON, Canada; Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, University of Western OntarioLondon, ON, Canada.
Western University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is characterized by motor symptoms, such as resting tremor, bradykinesia and rigidity, but also features non-motor complications. PD patients taking dopaminergic therapy, such as levodopa but especially dopamine agonists (DAs), evidence an increase in impulse control disorders (ICDs), suggesting a link between dopaminergic therapy and impulsive pursuit of pleasurable activities. However, impulsivity is a multifaceted construct. Motor impulsivity refers to the inability to overcome automatic responses or cancel pre-potent responses. Previous research has suggested that PD patients,

Indexed as

basal gangliaGo No-go taskhealthy subjectsmotor impulsivitypramipexolestriatum

Identifiers

PMID27803657
PMCPMC5067488
OpenAlexW2538692253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.