ArticleProceedings of the National Academy of Sciences of the United States of America2016
Rapid and independent memory formation in the parietal cortex.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 3 of them syntheses that pooled it.
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Who cites it
89 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Neural networks underlying magnitude perception: a specific meta-analysis of fMRI studies.Cerebral cortex (New York, N.Y. : 1991) · 2025Pooled it
- Photobiomodulation in the aging brain: a systematic review from animal models to humans.GeroScience · 2024Pooled it
- Impaired episodic memory in PTSD patients - A meta-analysis of 47 studies.Frontiers in psychiatry · 2022Pooled it
- Multi-networks connectivity at baseline predicts the clinical efficacy of left angular gyrus-navigated rTMS in the spectrum of Alzheimer's disease: A sham-controlled study.CNS neuroscience & therapeutics · 2023Trial
- Context-dependent abstraction of temporal relationships during naturalistic episodic memory.iScience · 2026Article
- Brain-cognition relationships and treatment outcome in treatment-resistant late-life depression.Nature communications · 2026Article
- Distinct Physiological Mechanisms Drive Grey Matter Plasticity in Complex Versus Simple Sequence Learning.Human brain mapping · 2026Article
- Neural population dynamics and temporal context cells in macaque medial parietal cortex support temporal order memory.PLoS biology · 2026Article
- Posterior parietal cortex oscillatory activity reflects persistent spatial memory impairments induced by early hippocampal amyloidosis in male mice.The Journal of physiology · 2026Article
- Altered rhythmic and arrhythmic electroencephalographic activity during non-rapid eye movement sleep in amnestic mild cognitive impairment.Brain communications · 2026Article
- Spatial contexts with reliable neural representations support reinstatement of subsequently placed objects.Nature human behaviour · 2026Article
- Gamma tACS over the prefrontal and parietal cortices enhances episodic memory performance.Frontiers in human neuroscience · 2026Article
- Neural correlates and reinstatement of recent and remote memory in children and young adults.eLife · 2025Article
- The cognitive neuroscience of memory representations.Neuroscience and biobehavioral reviews · 2025Review
- Prior text-based learning enhances the benefits of simulation-based learning on confidence and long-term recall.NPJ science of learning · 2025Article
- Longitudinal functional connectivity during rest and task is differentially related to Alzheimer's pathology and episodic memory in older adults.Scientific reports · 2025Article
- Neurocognitive and Resting-State Functional Magnetic Resonance Imaging Changes in Patients With Diffuse Gliomas After Chemoradiation Therapy.International journal of radiation oncology, biology, physics · 2025Article
- How sturdy is your memory palace? Reliable room representations predict subsequent reinstatement of placed objects.bioRxiv : the preprint server for biology · 2025Article
- Directed cell-type recruitment during consolidation of a remote memory.bioRxiv : the preprint server for biology · 2025Article
- Memory Boost for Recurring Emotional Events Is Driven by Initial Amygdala Response Promoting Stable Neocortical Patterns across Repetitions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous evidence indicates that the brain stores memory in two complementary systems, allowing both rapid plasticity and stable representations at different sites. For memory to be established in a long-lasting neocortical store, many learning repetitions are considered necessary after initial encoding into hippocampal circuits. To elucidate the dynamics of hippocampal and neocortical contributions to the early phases of memory formation, we closely followed changes in human functional brain activity while volunteers navigated through two different, initially unknown virtual environments. In one condition, they were able to encode new information continuously about the spatial layout of the maze. In the control condition, no information could be learned because the layout changed constantly. Our results show that the posterior parietal cortex (PPC) encodes memories for spatial locations rapidly, beginning already with the first visit to a location and steadily increasing activity with each additional encounter. Hippocampal activity and connectivity between the PPC and hippocampus, on the other hand, are strongest during initial encoding, and both decline with additional encounters. Importantly, stronger PPC activity related to higher memory-based performance. Compared with the nonlearnable control condition, PPC activity in the learned environment remained elevated after a 24-h interval, indicating a stable change. Our findings reflect the rapid creation of a memory representation in the PPC, which belongs to a recently proposed parietal memory network. The emerging parietal representation is specific for individual episodes of experience, predicts behavior, and remains stable over offline periods, and must therefore hold a mnemonic function.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.