Evidence map›Paper›PMID 27803155›Full record

ReviewEndocrine connections2016

Bridging the gap: metabolic and endocrine care of patients during transition.

Anita Hokken-Koelega, Aart-Jan van der Lely, Berthold Hauffa, Gabriele Häusler, Gudmundur Johannsson, Mohamad Maghnie, Jesús Argente, Jean DeSchepper, Helena Gleeson, John W Gregory and 11 more

Open access · goldAbstract readReview
In one paragraph

Review in Endocrine connections, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Approach to the Patient: Management of Pituitary Hormone Replacement Through Transition.The Journal of clinical endocrinology and metabolism · 2022
    Article
  12. Article
  13. Current concepts of the diagnosis of adult growth hormone deficiency.Reviews in endocrine & metabolic disorders · 2021
    Review
  14. Review
  15. Dietary Management for Adolescents with Prader-Willi Syndrome.Adolescent health, medicine and therapeutics · 2020
    Review
  16. Article
  17. Article
  18. Observational
  19. Review
  20. Three practical principles in planning and developing health care transition: our personal perspectives.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 4 countries.

Anita Hokken-KoelegaErasmus University Medical CentreRotterdam, The Netherlands.
Aart-Jan van der LelyErasmus University Medical CentreRotterdam, The Netherlands a.vanderlelij@erasmusmc.nl.
Berthold HauffaUniversity Children's HospitalEssen, Germany.
Gabriele HäuslerMedical University and General Hospital of ViennaVienna, Austria.
Gudmundur JohannssonSahlgrenska University HospitalGöteborg, Sweden.
Mohamad MaghnieIstituto Giannina GasliniUniversity of Genova, Genova, Italy.
Jesús ArgenteHospital Infantil Universitario Niño JesúsMadrid, Spain.
Jean DeSchepperUniversity Hospital BrusselsBrussels, Belgium.
Helena GleesonQueen Elizabeth HospitalBirmingham, UK.
John W GregoryCardiff University School of MedicineCardiff, UK.
Charlotte HöybyeDepartment of Molecular Medicine and SurgeryKarolinska Institute and Department of Endocrinology, Metabolism and Diabetology, Karolinska University Hospital, Stockholm, Sweden.
Fahrettin KeleştimurDepartment of EndocrinologySchool of Medicine, Erciyes University, Kayseri, Turkey.
Anton LugerSahlgrenska University HospitalGöteborg, Sweden.
Hermann L MüllerDepartment of PediatricsKlinikum Oldenburg, Medical Campus University Oldenburg, Oldenburg, Germany.
Sebastian NeggersUniversity Children's HospitalEssen, Germany.
Vera Popovic-BrkicBelgrade University School of MedicineBelgrade, Serbia.
Eleonora PorcuUniversity of BolognaBologna, Italy.
Lars SävendahlDepartment of Women's and Children's HealthKarolinska Institutet, and Pediatric Endocrinology Unit, Karolinska University Hospital, Stockholm, Sweden.
Stephen ShaletThe Christie HospitalManchester, UK.
Bessie SpiliotisUniversity of Patras School of MedicinePatras, Greece.
Maithé TauberHôpital des EnfantsToulouse, France.
Sahlgrenska University Hospital · SEUniversity Children's Hospital Tübingen · DEErasmus University Rotterdam · NLUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSeamless transition of endocrine patients from the paediatric to adult setting is still suboptimal, especially in patients with complex disorders, i.e., small for gestational age, Turner or Prader-Willi syndromes; Childhood Cancer Survivors, and those with childhood-onset growth hormone deficiency.

methodsAn expert panel meeting comprised of European paediatric and adult endocrinologists was convened to explore the current gaps in managing the healthcare of patients with endocrine diseases during transition from paediatric to adult care settings.

resultsWhile a consensus was reached that a team approach is best, discussions revealed that a 'one size fits all' model for transition is largely unsuccessful in these patients. They need more tailored care during adolescence to prevent complications like failure to achieve target adult height, reduced bone mineral density, morbid obesity, metabolic perturbations (obesity and body composition), inappropriate/inadequate puberty, compromised fertility, diminished quality of life and failure to adapt to the demands of adult life. Sometimes it is difficult for young people to detach emotionally from their paediatric endocrinologist and/or the abrupt change from an environment of parental responsibility to one of autonomy. Discussions about impending transition and healthcare autonomy should begin in early adolescence and continue throughout young adulthood to ensure seamless continuum of care and optimal treatment outcomes.

conclusionsEven amongst a group of healthcare professionals with a great interest in improving transition services for patients with endocrine diseases, there is still much work to be done to improve the quality of healthcare for transition patients.

Indexed as

developmentally appropriate healthcareGH therapymetabolic syndromequality of lifetransition

Identifiers

PMID27803155
PMCPMC5118971
OpenAlexW2344253850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.