Evidence map›Paper›PMID 27803044›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

Preclinical Evaluation of Chimeric Antigen Receptors Targeting CD70-Expressing Cancers.

Qiong J Wang, Zhiya Yu, Ken-Ichi Hanada, Krishna Patel, David Kleiner, Nicholas P Restifo, James C Yang

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 85 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Recent advances in CAR-T cell therapy for acute myeloid leukaemia.Journal of cellular and molecular medicine · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qiong J WangSurgery Branch and Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland. qiongwang@mail.nih.gov James_Yang@nih.gov.
Zhiya YuSurgery Branch and Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
Ken-Ichi HanadaSurgery Branch and Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
Krishna PatelSurgery Branch and Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
David KleinerSurgery Branch and Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
Nicholas P RestifoSurgery Branch and Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
James C YangSurgery Branch and Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland. qiongwang@mail.nih.gov James_Yang@nih.gov.
Center for Cancer Research · US

Funding

Building on the success of the adoptive immunotherapy of cancerZIABC010763 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ROSENBERG, STEVEN · 2009 to 2020
$25.0M
Generation of T-cell receptors recognizing antigens on non-melanoma tumorsZIABC011337 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI YANG, JAMES C · 2010 to 2025
$10.4M
STUDY OF INTERLEUKIN-2 BASED IMMUNOTHERAPYZ01SC006660 · SC · DIVISION OF CLINICAL SCIENCES - NCI · PI YANG, JAMES C · 1996 to 2008
$1.8M
Intramural NIH HHS Z01 SC006660Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCD27 LigandCD28 AntigensCD3 ComplexCell Line, TumorHumansImmunotherapy, AdoptiveLymphocyte ActivationMiceNeoplasmsReceptors, Antigen, T-CellSignal TransductionTumor Necrosis Factor Receptor Superfamily, Member 7Xenograft Model Antitumor AssaysCD27 LigandCD28 AntigensCD3 ComplexCD70 protein, humanReceptors, Antigen, T-CellTumor Necrosis Factor Receptor Superfamily, Member 7

Identifiers

PMID27803044
PMCPMC5411349
OpenAlexW2547869005

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.