ArticleBMJ case reports2016
When plenty is too much: water intoxication in a patient with a simple urinary tract infection.
Article in BMJ case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Clinical characteristics and outcomes of hyponatraemia associated with oral water intake in adults: a systematic review.BMJ open · 2021Pooled it
- Comparison of body water status and its distribution in patients with non-septic infection, patients with sepsis, and healthy controls.Clinical and experimental emergency medicine · 2021Article
- A Subset of Primary Polydipsia, "Dipsogneic Diabetes Insipidus", in Apparently Healthy People Due to Excessive Water Intake: Not Enough Light to Illuminate the Dark Tunnel.Healthcare (Basel, Switzerland) · 2021Review
- PURL: Can drinking more water prevent urinary tract infections?The Journal of family practice · 2020Article
- Review
- Acute Dysnatremias - a dangerous and overlooked clinical problem.Scandinavian journal of trauma, resuscitation and emergency medicine · 2019Review
- Observational study of the effects of upper respiratory tract infection on hydration status.Multidisciplinary respiratory medicine · 2019Article
- Postmortem diagnosis of hyponatremia: case report and literature review.International journal of legal medicine · 2018Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Healthcare professionals frequently advise patients with simple infective illness to drink more fluids. Here, a 59-year-old woman with a urinary tract infection followed such advice resulting in hospital admission with symptomatic acute hyponatraemia. Water intoxication is well recognised as a cause of symptomatic hyponatraemia in endurance sports, MDMA use and psychogenic polydipsia. It has rarely been described outside of these circumstances. With normal renal function, it is difficult to overwhelm the excretory capacity for water. However, in infective illness, increased levels of antidiuretic hormones (which may be secreted both appropriately to correct volume status and inappropriately as a feature of disease) reduce renal excretion of water. In this scenario, could increased administration of oral hypotonic fluids lead to hyponatraemia, with associated morbidity and mortality, than has previously been recognised? There is a need for more research to qualify our oft-given advise to drink more fluids.
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