Evidence map›Paper›PMID 27802838›Full record

ArticleBMC pharmacology & toxicology2016

Chronic early life lead (Pb

Sara Rose Guariglia, Kirstie H Stansfield, Jennifer McGlothan, Tomas R Guilarte

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pharmacology & toxicology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The Effect of Lead Exposure on Autism Development.International journal of molecular sciences · 2021
    Review
  2. Lead-induced changes of cytoskeletal protein is involved in the pathological basis in mice brain.Environmental science and pollution research international · 2018
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sara Rose GuarigliaDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY, 10032, USA.
Kirstie H StansfieldDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY, 10032, USA.
Jennifer McGlothanDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY, 10032, USA.
Tomas R GuilarteDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY, 10032, USA. tguilart@fiu.edu.

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
NMDA RECEPTOR FUNCTION IN LEAD NEUROTOXICITYR01ES006189 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI GUILARTE, TOMAS R · 1993 to 2019
$9.3M
Presynaptic Mechanisms of Lead NeurotoxicityR01ES020465 · NIEHS · FLORIDA INTERNATIONAL UNIVERSITY · PI GUILARTE, TOMAS R · 2012 to 2016
$2.5M
NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R01 ES006189NIEHS NIH HHS R01 ES020465
6 · The paper itself

Abstract

backgroundLead (Pb

methodsIn the present study, we used transmission electron microscopy to examine presynaptic vesicle pools in Mossy Fiber-CA3 synapses and in Perforant Path-Dentate Gyrus synapses of rats to determine if in vivo Pb

resultsWe found that Pb

conclusionsIn our previous work, we have demonstrated that Pb

Indexed as

Age FactorsAnimalsDrug Administration ScheduleHippocampusLeadMalePresynaptic TerminalsRandom AllocationRatsRats, Long-EvansSynapsesSynaptic VesiclesLeadLead (Pb2+)MitochondriaPostsynaptic Density (PSD)PresynapticSynapsesVesicles

Identifiers

PMID27802838
PMCPMC5090882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.