Evidence map›Paper›PMID 27801863›Full record

ArticleNutrients2016

Nutrient Transporter Expression in the Jejunum in Relation to Body Mass Index in Patients Undergoing Bariatric Surgery.

Brian A Irving, G Craig Wood, Peter N Bennotti, Ellappan Babu, Abhishek Deshpande, Michelle R Lent, Anthony Petrick, Jon Gabrielsen, William Strodel, Glenn S Gerhard and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Brian A IrvingObesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA 17822, USA. brianairving@lsu.edu.
G Craig WoodObesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA 17822, USA. cwood@geisinger.edu.
Peter N BennottiObesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA 17822, USA. pbenotti64@gmail.com.
Ellappan BabuDepartment of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. babu.ellappan@ttuhsc.edu.
Abhishek DeshpandeMedicine Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA. abhishekdp@gmail.com.
Michelle R LentObesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA 17822, USA. mrlent@geisinger.edu.
Anthony PetrickSurgery, Geisinger Health System, 100 N Academy Ave, Danville, PA 17822, USA. atpetrick@geisinger.edu.
Jon GabrielsenSurgery, Geisinger Health System, 100 N Academy Ave, Danville, PA 17822, USA. jdgabrielsen@geisinger.edu.
William StrodelSurgery, Geisinger Health System, 100 N Academy Ave, Danville, PA 17822, USA. westrodel@geisinger.edu.
Glenn S GerhardObesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA 17822, USA. gsgerhard@temple.edu.
Christopher D StillObesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA 17822, USA. cstill@geisinger.edu.
Vadivel GanapathyDepartment of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. vadivel.ganapathy@ttuhsc.edu.
David D K RolstonObesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA 17822, USA. ddrolston@geisinger.edu.
Geisinger Health System · USTexas Tech University · USCleveland Clinic · US

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
TECHNOLOGY NMR SPECTROSCOPYU24DK100469 · NIDDK · MAYO CLINIC ROCHESTER · PI NAIR, K SREEKUMARAN · 2013 to 2017
$9.0M
Genetic Determinants of Weight Loss and Resolution of Co-MorbiditiesR01DK088231 · NIDDK · TEMPLE UNIV OF THE COMMONWEALTH · PI GERHARD, GLENN S · 2011 to 2015
$2.5M
SLC5A8 is a conditional tumor suppressor in colon linked to dietary fiber contentR01CA190710 · NCI · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI GANAPATHY, VADIVEL · 2015 to 2019
$1.8M
NCATS NIH HHS UL1 TR000135NCI NIH HHS R01 CA190710NIDDK NIH HHS P30 DK072488NIDDK NIH HHS R01 DK088231NIDDK NIH HHS U24 DK100469
6 · The paper itself

Abstract

Nutrient tranters (NT) facilitate nutrient absorption and contribute to the regulation of circulating nutrients. In this cross-sectional study, we determined the associations between the level of obesity; mRNA abundance for NTs; and serum concentrations of amino acids, short-chain fatty acids, and glucose in patients with morbid obesity undergoing a Roux-en-Y gastric bypass. Proximal jejunal samples were obtained at the time of surgery from 42 patients (90% female, age = 42.6 ± 11.9 years, pre-operative body mass index (BMI) = 55.5 ± 11.3 kg/m²) undergoing a Roux-en-Y gastric bypass. RNA was extracted from the jejunal mucosa and quantitative real-time-PCR was performed for the NTs studied. BMI negatively correlated with jejunal mRNA abundance of the amino acid NTs

Indexed as

Gene Expression RegulationAdultBody Mass IndexCohort StudiesComorbidityCross-Sectional StudiesFatty Acids, VolatileFemaleGastric BypassHumansIntestinal MucosaJejunumMaleMembrane Transport ProteinsMiddle AgedMonocarboxylic Acid TransportersFatty Acids, VolatileMembrane Transport ProteinsMonocarboxylic Acid TransportersRNA, MessengerSLC5A8 protein, humangastrointestinal tractmorbid obesitynutrient absorptionnutrient transportersobesity

Identifiers

PMID27801863
PMCPMC5133071
OpenAlexW2542935288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.