Evidence map›Paper›PMID 27801807›Full record

ArticleMolecules (Basel, Switzerland)2016

Alkaloids with Activity against the Zika Virus Vector Aedes aegypti (L.)-Crinsarnine and Sarniensinol, Two New Crinine and Mesembrine Type Alkaloids Isolated from the South African Plant Nerine sarniensis.

Marco Masi, Antonio Cala, Nurhayat Tabanca, Alessio Cimmino, Ivan R Green, Jeffrey R Bloomquist, Willem A L van Otterlo, Francisco A Macias, Antonio Evidente

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Potential Antiviral Compounds fromMolecules (Basel, Switzerland) · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Plant Natural Products for the Control ofMolecules (Basel, Switzerland) · 2020
    Review
  10. The GenusMolecules (Basel, Switzerland) · 2019
    Review
  11. Chemical composition of the essential oil andSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2019
    Article
  12. Article
  13. Lycorine: A prospective natural lead for anticancer drug discovery.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2018
    Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marco MasiDepartment of Chemical Sciences, University of Naples "Federico II", Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Napoli, Italy. marco.masi@unina.it.
Antonio CalaDepartment of Chemical Sciences, University of Naples "Federico II", Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Napoli, Italy. antonio.cala@uca.es.
Nurhayat TabancaDepartment of Entomology and Nematology, Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA. ntabanca@ufl.edu.
Alessio CimminoDepartment of Chemical Sciences, University of Naples "Federico II", Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Napoli, Italy. alessio.cimmino@unina.it.
Ivan R GreenDepartment of Chemistry and Polymer Science, University of Stellenbosch, Private Bag X1, Matieland, 7602 Stellenbosch, South Africa. irg@sun.ca.za.
Jeffrey R BloomquistDepartment of Entomology and Nematology, Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA. jbquist@epi.ufl.edu.
Willem A L van OtterloU.S. Department of Agriculture-Agricultural Research Service, Subtropical Horticulture Research Station, 13601 Old Cutler Rd., Miami, FL 33158, USA. wvo@sun.ca.za.
Francisco A MaciasAllelopathy Group, Department of Organic Chemistry, School of Science, Institute of Biomolecules (INBIO), University of Cádiz, C/República Saharaui 7, 11510 Puerto Real, Cádiz, Spain. famacias@uca.es.
Antonio EvidenteDepartment of Chemical Sciences, University of Naples "Federico II", Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Napoli, Italy. evidente@unina.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two new Amaryllidaceae alkaloids, belonging to the mesembrine- and crinine-types, named crinsarnine (

Indexed as

AedesAlkaloidsInsecticidesInsect VectorsZika VirusAnimalsMagnoliopsidaAlkaloidsInsecticidesAedes aegyptiAmaryllidaceaebowdensinecrininecrinsarninemesembrineNerine sarniensissarniensinolZika virus

Identifiers

PMID27801807
PMCPMC6273414

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.