Evidence map›Paper›PMID 27801805›Full record

ArticleInternational journal of molecular sciences2016

Urinary Angiotensinogen Could Be a Prognostic Marker of the Renoprotection of Olmesartan in Metabolic Syndrome Patients.

Tomoko Mizushige, Hiroyuki Kobori, Hirofumi Hitomi, Yoko Nishijima, Fumihiro Tomoda, Satoshi Morimoto, Masakazu Kohno, Akira Nishiyama

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Tomoko MizushigeDepartment of Pharmacology, Kagawa University School of Medicine, Kagawa 761-0793, Japan. m01084tm@jichi.ac.jp.
Hiroyuki KoboriDepartment of Pharmacology, Kagawa University School of Medicine, Kagawa 761-0793, Japan. hkobori@iuhw.ac.jp.
Hirofumi HitomiDepartment of Pharmacology, Kagawa University School of Medicine, Kagawa 761-0793, Japan. hitomi@med.kagawa-u.ac.jp.
Yoko NishijimaDepartment of Medicine, Kagawa University School of Medicine, Kagawa 761-0793, Japan. youko.n@med.kagawa-u.ac.jp.
Fumihiro TomodaThe Second Department of Internal Medicine, Toyama University School of Medicine, Toyama 930-0194, Japan. tomoda@med.u-toyama.ac.jp.
Satoshi MorimotoThe Second Department of Internal Medicine, Kansai Medical University, Osaka 573-1010, Japan. smorimoto@endm.twmu.ac.jp.
Masakazu KohnoDepartment of Medicine, Kagawa University School of Medicine, Kagawa 761-0793, Japan. mkohno@med.kagawa-u.ac.jp.
Akira NishiyamaDepartment of Pharmacology, Kagawa University School of Medicine, Kagawa 761-0793, Japan. akira@med.kagawa-u.ac.jp.
Kagawa University · JPKansai Medical University · JPTulane University · USUniversity of Toyama · JP

Funding

Intrarenal Augmentation of Angiotensinogen by Ang IIR01DK072408 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI NAVAR, LUIS GABRIEL · 2006 to 2010
$1.2M
NIDDK NIH HHS R01 DK072408
6 · The paper itself

Abstract

This study was performed to demonstrate urinary angiotensinogen as a potential prognostic marker of the albuminuria reduction effects of olmesartan in patients with metabolic syndrome. In 24 patients (eight women, 57.88 ± 2.00 years), 5-40 mg/day of olmesartan were given. Urinary concentrations of albumin and angiotensinogen (normalized by urinary concentrations of creatinine) and plasma renin activity were measured before and after the 12- and 24-week marks of olmesartan treatment. Olmesartan treatment increased plasma renin activity and decreased urinary albumin and urinary angiotensinogen significantly (

Indexed as

AdultAlbuminuriaAngiotensinogenBiomarkers, PharmacologicalCreatinineFemaleHumansImidazolesMaleMetabolic SyndromeMiddle AgedPrognosisTetrazolesAngiotensinogenBiomarkers, PharmacologicalCreatinineImidazolesolmesartanTetrazolesangiotensin receptor blockermetabolic syndromeprognostic marker of albuminuria reduction effectsrenin-angiotensin systemurinary angiotensinogen

Identifiers

PMID27801805
PMCPMC5133801
OpenAlexW2544208224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.