Evidence map›Paper›PMID 27801785›Full record

ArticleMarine drugs2016

Novel Conopeptides of Largely Unexplored Indo Pacific Conus sp.

Eline K M Lebbe, Maarten G K Ghequire, Steve Peigneur, Bea G Mille, Prabha Devi, Samuthirapandian Ravichandran, Etienne Waelkens, Lisette D'Souza, René De Mot, Jan Tytgat

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. In the picture: disulfide-poor conopeptides, a class of pharmacologically interesting compounds.The journal of venomous animals and toxins including tropical diseases · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Eline K M LebbeToxicology and Pharmacology, KU Leuven, Campus Gasthuisberg, O & N2, Herestraat 49, P.O. Box 922, 3000 Leuven, Belgium. eline.lebbe@pharm.kuleuven.be.
Maarten G K GhequireCentre of Microbial and Plant Genetics, KU Leuven, Kasteelpark Arenberg 20, P.O. Box 2460, 3001 Heverlee, Belgium. maarten.ghequire@biw.kuleuven.be.
Steve PeigneurToxicology and Pharmacology, KU Leuven, Campus Gasthuisberg, O & N2, Herestraat 49, P.O. Box 922, 3000 Leuven, Belgium. steve.peigneur@pharm.kuleuven.be.
Bea G MilleToxicology and Pharmacology, KU Leuven, Campus Gasthuisberg, O & N2, Herestraat 49, P.O. Box 922, 3000 Leuven, Belgium. bea.mille@vib-kuleuven.be.
Prabha DeviCSIR-National Institute of Oceanography, 403 004 Dona Paula, Goa, India. dprabha@nio.org.
Samuthirapandian RavichandranCenter of Advanced Study in Marine Biology, Annamalai University, 608 502 Parangipettai, Tamil Nadu, India. sravicas@gmail.com.
Etienne WaelkensLaboratory for Protein Phosphorylation and Proteomics, KU Leuven, O & N1 Herestraat 49, P.O. Box 901, 3000 Leuven, Belgium. etienne.waelkens@med.kuleuven.be.
Lisette D'SouzaCSIR-National Institute of Oceanography, 403 004 Dona Paula, Goa, India. lisette@nio.org.
René De MotCentre of Microbial and Plant Genetics, KU Leuven, Kasteelpark Arenberg 20, P.O. Box 2460, 3001 Heverlee, Belgium. rene.demot@biw.kuleuven.be.
Jan TytgatToxicology and Pharmacology, KU Leuven, Campus Gasthuisberg, O & N2, Herestraat 49, P.O. Box 922, 3000 Leuven, Belgium. jan.tytgat@pharm.kuleuven.be.
KU Leuven · BENational Institute of Oceanography · INAnnamalai University · INVIB-KU Leuven Center for Microbiology · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cone snails are predatory creatures using venom as a weapon for prey capture and defense. Since this venom is neurotoxic, the venom gland is considered as an enormous collection of pharmacologically interesting compounds having a broad spectrum of targets. As such, cone snail peptides represent an interesting treasure for drug development. Here, we report five novel peptides isolated from the venom of

Indexed as

Amino Acid SequenceAnimalsAnti-Bacterial AgentsAntifungal AgentsCholinesterase InhibitorsConotoxinsConus SnailDisulfidesGram-Negative BacteriaGram-Positive BacteriaMicrobial Sensitivity TestsMollusk VenomsOocytesPacific OceanPeptidesPotassium Channel BlockersAnti-Bacterial AgentsAntifungal AgentsCholinesterase InhibitorsConotoxinsDisulfidesMollusk VenomsPeptidesPotassium Channel BlockersSodium Channel Blockersantimicrobial testsconotoxinConuselectrophysiologypeptide characterization

Identifiers

PMID27801785
PMCPMC5128742
OpenAlexW2540352200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.