Evidence map›Paper›PMID 27801783›Full record

ArticleInternational journal of molecular sciences2016

Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.

Jen-Jie Lin, Robert Y L Wang, Jiing-Chuan Chen, Chien-Chih Chiu, Ming-Hui Liao, Yu-Jen Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. 4-Carbomethoxyl-10-Epigyrosanoldie E Extracted from Cultured Soft CoralOxidative medicine and cellular longevity · 2022
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. The Effect of BornylInternational journal of molecular sciences · 2018
    Article
  11. Insights into the Roles of Midazolam in Cancer Therapy.Evidence-based complementary and alternative medicine : eCAM · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jen-Jie LinGraduate Institute of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan. q87634@hotmail.com.
Robert Y L WangDepartment of Biomedical Sciences and Molecular Medicine Research Center, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan. yuwang@mail.cgu.edu.tw.
Jiing-Chuan ChenDepartment of Food Science and Nutrition, Meiho University, Pingtung 91202, Taiwan. x00000017@meiho.edu.tw.
Chien-Chih ChiuDepartment of Biotechnology, Kaohsiung Medical University, Kaohsiung 80708, Taiwan. woodnettle2002@gmail.com.
Ming-Hui LiaoGraduate Institute of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan. mhliao@mail.npust.edu.tw.
Yu-Jen WuDepartment of Food Science and Nutrition, Meiho University, Pingtung 91202, Taiwan. wyr924@ms24.hinet.net.
Meiho University · TWNational Pingtung University of Science and Technology · TWChang Gung University · TWKaohsiung Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural compounds from soft corals have been increasingly used for their antitumor therapeutic properties. This study examined 11-

Indexed as

AnimalsAnthozoaAnthracenesApoptosisCarcinoma, HepatocellularCell ProliferationCell SurvivalCinnamatesDiterpenesEndoplasmic Reticulum StressGene Expression Regulation, NeoplasticHumansJNK Mitogen-Activated Protein KinasesLiver NeoplasmsMitochondriaSignal TransductionAnthracenesCinnamatesDDIT3 protein, humanDiterpenesJNK Mitogen-Activated Protein KinasespyrazolanthronesalubrinalsinulariolideThioureaTranscription Factor CHOP11-epi-sinulariolide acetateantitumorER stresshepatocellular carcinomamitochondrial dysfunction

Identifiers

PMID27801783
PMCPMC5133788
OpenAlexW2542945307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.