Evidence map›Paper›PMID 27801717›Full record

ArticleNursing research

Which Propensity Score Method Best Reduces Confounder Imbalance? An Example From a Retrospective Evaluation of a Childhood Obesity Intervention.

Krista Schroeder, Haomiao Jia, Arlene Smaldone

Open access · greenAbstract readComparative Study
In one paragraph

Article in Nursing research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Krista SchroederKrista Schroeder, PhD, RN, CCRN, is Postdoctoral Fellow, University of Pennsylvania School of Nursing, Philadelphia. Haomiao Jia, PhD, is Associate Professor of Biostatistics, Columbia University School of Nursing, New York, New York. Arlene Smaldone, PhD, CPNP, CDE, is Associate Professor of Nursing and Dental Behavioral Sciences and Assistant Dean of Scholarship and Research, Columbia University School of Nursing, New York, New York.
Haomiao Jia
Arlene Smaldone
Apple (Israel) · IL

Funding

Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
RESEARCH ON VULNERABLE WOMEN CHILDREN AND FAMILIEST32NR007100 · NINR · UNIVERSITY OF PENNSYLVANIA · PI MEDOFF-COOPER, BARBARA S · 1998 to 2018
$7.2M
Systems Science and Comparative and Cost-Effectiveness Research Training for Nurse Scientists (S2CER2)T32NR014205 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Lusine Poghosyan, Jingjing Shang · 2013 to 2026
$4.2M
NCATS NIH HHS UL1 TR000040NINR NIH HHS T32 NR007100NINR NIH HHS T32 NR014205
6 · The paper itself

Abstract

backgroundPropensity score (PS) methods are increasingly being employed by researchers to reduce bias arising from confounder imbalance when using observational data to examine intervention effects.

objectiveThe purpose of this study was to examine PS theory and methodology and compare application of three PS methods (matching, stratification, weighting) to determine which best improves confounder balance.

methodsBaseline characteristics of a sample of 20,518 school-aged children with severe obesity (of whom 1,054 received an obesity intervention) were assessed prior to PS application. Three PS methods were then applied to the data to determine which showed the greatest improvement in confounder balance between the intervention and control group. The effect of each PS method on the outcome variable-body mass index percentile change at one year-was also examined. SAS 9.4 and Comprehensive Meta-analysis statistical software were used for analyses.

resultsPrior to PS adjustment, the intervention and control groups differed significantly on seven of 11 potential confounders. PS matching removed all differences. PS stratification and weighting both removed one difference but created two new differences. Sensitivity analyses did not change these results. Body mass index percentile at 1 year decreased in both groups. The size of the decrease was smaller in the intervention group, and the estimate of the decrease varied by PS method. DISCUSSION: Selection of a PS method should be guided by insight from statistical theory and simulation experiments, in addition to observed improvement in confounder balance. For this data set, PS matching worked best to correct confounder imbalance. Because each method varied in correcting confounder imbalance, we recommend that multiple PS methods be compared for ability to improve confounder balance before implementation in evaluating treatment effects in observational data.

Indexed as

Confounding Factors, EpidemiologicPediatric ObesityPropensity ScoreAdolescentBiasBiomedical ResearchChildFemaleHumansMaleModels, TheoreticalRetrospective Studies

Identifiers

PMID27801717
PMCPMC5098456
OpenAlexW2546808655

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.