Evidence map›Paper›PMID 27801680›Full record

ArticleThe Journal of clinical investigation2016

Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency.

Jolan E Walter, Lindsey B Rosen, Krisztian Csomos, Jacob M Rosenberg, Divij Mathew, Marton Keszei, Boglarka Ujhazi, Karin Chen, Yu Nee Lee, Irit Tirosh and 47 more

Abstract readPublished Erratum
In one paragraph

Article in The Journal of clinical investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  10. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

57 authors.

Jolan E Walter
Lindsey B Rosen
Krisztian Csomos
Jacob M Rosenberg
Divij Mathew
Marton Keszei
Boglarka Ujhazi
Karin Chen
Yu Nee Lee
Irit Tirosh
Kerry Dobbs
Waleed Al-Herz
Morton J Cowan
Jennifer Puck
Jack J Bleesing
Michael S Grimley
Harry Malech
Suk See De Ravin
Andrew R Gennery
Roshini S Abraham
Avni Y Joshi
Thomas G Boyce
Manish J Butte
Kari C Nadeau
Imelda Balboni
Kathleen E Sullivan
Javeed Akhter
Mehdi Adeli
Reem A El-Feky
Dalia H El-Ghoneimy
Ghassan Dbaibo
Rima Wakim
Chiara Azzari
Paolo Palma
Caterina Cancrini
Kelly Capuder
Antonio Condino-Neto
Beatriz T Costa-Carvalho
Joao Bosco Oliveira
Chaim Roifman
David Buchbinder
Attila Kumanovics
Jose Luis Franco
Tim Niehues
Catharina Schuetz
Taco Kuijpers
Christina Yee
Janet Chou
Michel J Masaad
Raif Geha
Gulbu Uzel
Rebecca Gelman
Steven M Holland
Mike Recher
Paul J Utz
Sarah K Browne
Luigi D Notarangelo

Funding

Gene Therapy Basic Research to Treat Inherited Primary Immune DeficienciesZIAAI000644 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MALECH, HARRY L · 2009 to 2025
$12.1M
Development and Clinical Application of Gene and Cell therapies for Patients with Immune DeficienciesZIAAI000645 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI DE RAVIN, SUK SEE · 2009 to 2025
$10.1M
Modeling and correcting human SCID using patient-derived iPS cellsR01AI100887 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI MANIS, JOHN P · 2012 to 2020
$4.5M
Autoimmunity in Rag Deficiency: A Nexus of Immunodeficiency and DysregulationK08AI103035 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI WALTER, JOLAN ESZTER · 2012 to 2016
$683k
NIAID NIH HHS K08 AI103035NIAID NIH HHS R01 AI100887
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID27801680
PMCPMC5096894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.