Evidence map›Paper›PMID 27800584›Full record

ReviewSeminars in immunopathology2017

Neuroimmune interactions: dendritic cell modulation by the sympathetic nervous system.

Maisa C Takenaka, Marcia G Guereschi, Alexandre S Basso

Abstract readReview
PubMed Publisher
In one paragraph

Review in Seminars in immunopathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

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  10. Neuronal-Immune Cell Units in Allergic Inflammation in the Nose.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Peripheral neuroimmune interactions: selected review and some clinical implications.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021
    Review
  16. Review
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maisa C TakenakaDepartamento de Microbiologia, Imunologia e Parasitologia, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), Rua Botucatu 862, Edifício de Ciências Biomédicas 4° andar, São Paulo, SP, 04023-062, Brazil.
Marcia G GuereschiDepartamento de Microbiologia, Imunologia e Parasitologia, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), Rua Botucatu 862, Edifício de Ciências Biomédicas 4° andar, São Paulo, SP, 04023-062, Brazil.
Alexandre S BassoDepartamento de Microbiologia, Imunologia e Parasitologia, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), Rua Botucatu 862, Edifício de Ciências Biomédicas 4° andar, São Paulo, SP, 04023-062, Brazil. asbasso@unifesp.br.
Universidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cells are of paramount importance bridging innate and adaptive immune responses. Depending on the context, after sensing environmental antigens, commensal microorganisms, pathogenic agents, or antigens from the diet, dendritic cells may drive either different effector adaptive immune responses or tolerance, avoiding tissue damage. Although the plasticity of the immune response and the capacity to regulate itself are considered essential to orchestrate appropriate physiological responses, it is known that the nervous system plays a relevant role controlling immune cell function. Dendritic cells present in the skin, the intestine, and lymphoid organs, besides expressing adrenergic receptors, can be reached by neurotransmitters released by sympathetic fibers innervating these tissues. These review focus on how neurotransmitters from the sympathetic nervous system can modulate dendritic cell function and how this may impact the immune response and immune-mediated disorders.

Indexed as

NeuroimmunomodulationAnimalsCytokinesDendritic CellsHumansImmune SystemIntestinal MucosaIntestinesLymphoid TissueNorepinephrineReceptors, AdrenergicSignal TransductionSkinSympathetic Nervous SystemCytokinesNorepinephrineReceptors, AdrenergicCytokinesDendritic cellsNeuroimmune interactionsNoradrenalineSympathetic nervous system

Identifiers

PMID27800584
OpenAlexW2540712644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.