ArticleOpen forum infectious diseases2016
Increasing Infectious Endocarditis Admissions Among Young People Who Inject Drugs.
Article in Open forum infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05156437 (Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse), which is not on this map. Cited by 216 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL)
Who cites it
216 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Controlled-release hydromorphone and risk of infection in adults: a systematic review.Harm reduction journal · 2023Pooled it
- Validity of International Classification of Diseases codes in identifying illicit drug use target conditions using medical record data as a reference standard: A systematic review.Drug and alcohol dependence · 2020Pooled it
- Drug Use and Postoperative Mortality Following Valve Surgery for Infective Endocarditis: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Pooled it
- Examining the benefit of a higher maintenance dose of extended-release buprenorphine in opioid-injecting participants treated for opioid use disorder.Harm reduction journal · 2023Trial
- Substance Use Disorder Detection Rates Among Providers of General Medical Inpatients.Journal of general internal medicine · 2021Trial
- Opioid withdrawal symptoms, frequency, and pain characteristics as correlates of health risk among people who inject drugs.Drug and alcohol dependence · 2020Trial
- Trial
- Implementing Motivational Interviewing for Substance Misuse on Medical Inpatient Units: a Randomized Controlled Trial.Journal of general internal medicine · 2019Trial
- Tricuspid Valve Infective Endocarditis Seen on Point-of-Care Ultrasound: A Case Report.Cureus · 2026Article
- Infective Endocarditis in Ireland: A Nationwide Analysis.Journal of clinical medicine · 2026Article
- Valve-Specific Anatomy and Structural Determinants of Susceptibility to Infective Endocarditis: A Review.Journal of clinical medicine · 2026Review
- Tricuspid Valve Infective Endocarditis.Cureus · 2026Article
- Outcomes of a Program to Support Outpatient Antibiotic Adherence Among People Experiencing Housing Instability With Serious Injection Drug-Related Infections in Boston, MA: A Propensity Score Matched Study.Open forum infectious diseases · 2026Article
- Valve-specific structural vulnerability in infective endocarditis: a narrative review of surgical complexity and outcomes.Journal of cardiothoracic surgery · 2026Review
- Changing Patterns in Infective Endocarditis: A Contemporary Epidemiological Perspective.Pathogens (Basel, Switzerland) · 2026Review
- Recent hydromorphone injection and risk of incident infective endocarditis among people who inject drugs in Toronto, Canada: a cohort study.Harm reduction journal · 2026Article
- Transthoracic echocardiography in children withBMJ paediatrics open · 2026Article
- Insurance Status and Quality of Care in Infective Endocarditis: A National Analysis of Disparities in Length of Stay, Discharge, and Mortality.Journal of clinical medicine · 2026Article
- Outcomes and financial comparison of percutaneous debulking versus surgical management of tricuspid endocarditis.Journal of cardiothoracic surgery · 2026Article
- Temporal trends in mortality related to infective endocarditis and stroke in the United States.Global cardiology science & practice · 2026Article
156 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
People who inject drugs (PWID) are at risk for infective endocarditis (IE). Hospitalization rates related to misuse of prescription opioids and heroin have increased in recent years, but there are no recent investigations into rates of hospitalizations from injection drug use-related IE (IDU-IE). Using the Health Care and Utilization Project National Inpatient Sample (HCUP-NIS) dataset, we found that the proportion of IE hospitalizations from IDU-IE increased from 7% to 12.1% between 2000 and 2013. Over this time period, we detected a significant increase in the percentages of IDU-IE hospitalizations among 15- to 34-year-olds (27.1%-42.0%;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.