Evidence map›Paper›PMID 27800521›Full record

ArticleOpen forum infectious diseases2016

Continued Elevation of Interleukin-18 and Interferon-γ After Initiation of Antiretroviral Therapy and Clinical Failure in a Diverse Multicountry Human Immunodeficiency Virus Cohort.

Ashwin Balagopal, Nikhil Gupte, Rupak Shivakoti, Andrea L Cox, Wei-Teng Yang, Sima Berendes, Noluthando Mwelase, Cecilia Kanyama, Sandy Pillay, Wadzanai Samaneka and 16 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. A SpecificFrontiers in immunology · 2020
    Trial
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  3. Review
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  13. Common Variation inOpen forum infectious diseases · 2018
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Ashwin BalagopalJohns Hopkins University School of Medicine , Baltimore, Maryland.
Nikhil GupteJohns Hopkins University School of Medicine , Baltimore, Maryland.
Rupak ShivakotiJohns Hopkins University School of Medicine , Baltimore, Maryland.
Andrea L CoxJohns Hopkins University School of Medicine , Baltimore, Maryland.
Wei-Teng YangJohns Hopkins University School of Medicine , Baltimore, Maryland.
Sima BerendesMalawi College of Medicine-Johns Hopkins University Research Project , Blantyre , Malawi.
Noluthando MwelaseUniversity of Witwatersrand , Johannesburg , South Africa.
Cecilia KanyamaUniversity of North Carolina Project, Kamuzu Central Hospital , Lilongwe , Malawi.
Sandy PillayNelson Mandela School of Medicine , University of KwaZulu-Natal , Durban , South Africa.
Wadzanai SamanekaUniversity of Zimbabwe, College of Health Sciences , Harare.
Breno SantosHospital Nossa Senhora de Conceição , Porto Alegre , Brazil.
Selvamuthu PoongulaliY.R.G.Care , Chennai , India.
Srikanth TripathyNational AIDS Research Institute , Pune , India.
Cynthia RiviereLes Centres GHESKIO , Port-Au-Prince , Haiti.
Javier R LamaAsociación Civil Impacta Salud y Educación (IMPACTA) Peru Clinical Trials Unit , Lima.
Sandra W CardosoInstituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz , Rio de Janeiro , Brazil.
Patcharaphan SugandhavesaResearch Institute for Health Sciences, Chinag Mai University, Thailand.
Richard D SembaJohns Hopkins University School of Medicine , Baltimore, Maryland.
James HakimUniversity of Zimbabwe, College of Health Sciences , Harare.
Mina C HosseinipourUniversity of North Carolina Project, Kamuzu Central Hospital, Lilongwe, Malawi; University of North Carolina, Chapel Hill.
Nagalingeswaran KumarasamyY.R.G.Care , Chennai , India.
Ian SanneUniversity of Witwatersrand , Johannesburg , South Africa.
David AsmuthUniversity of California Davis, Sacramento.
Thomas CampbellUniversity of Colorado School of Medicine, Colorado.
Robert C BollingerJohns Hopkins University School of Medicine , Baltimore, Maryland.
Amita GuptaJohns Hopkins University School of Medicine , Baltimore, Maryland.

Funding

Leadership and Operations Center (LOC), AIDS Clinical Trials Group (ACTG); LOC 1/UM1AI068636 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, RAJESH T GANDHI · 2011 to 2026
$1073.1M
Statistical and Data Management Center (SDMC), AIDS Clinical Trials Group (ACTG)UM1AI068634 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Marlene Ann Cooper, Michael David Hughes · 2011 to 2026
$246.6M
AIDS Clinical Trials Group NetworkU01AI068636 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI KURITZKES, DANIEL R. · 2006 to 2010
$147.1M
Statistical and Data Management Center for the AIDS Clinical Trials GroupU01AI068634 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI HUGHES, MICHAEL DAVID · 2006 to 2010
$71.9M
University of North Carolina Global HIV Prevention and Treatment Clinical Trials Unit 2024 SupplementUM1AI069423 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, MINA CHRISTINE HOSSEINIPOUR · 2012 to 2026
$71.8M
UCSD Department of Medicine HIV/AIDS Clinical Trials UnitUM1AI069432 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TIMOTHY J. WILKIN · 2012 to 2026
$50.4M
Wits HIV Research Group CLINICAL TRIAL UNIT (CTU) reapplicationUM1AI069463 · NIAID · WITS HEALTH CONSORTIUM (PTY), LTD · PI REES, HELEN, SANNE, IAN MATTHIAS · 2012 to 2025
$31.8M
The Progression of Hepatitis C Among IDUs with HIVR01DA016078 · NIDA · JOHNS HOPKINS UNIVERSITY · PI BALAGOPAL, ASHWIN, THOMAS, DAVID L · 2002 to 2016
$10.9M
Colorado AIDS Clinical Trials UnitU01AI069450 · NIAID · UNIVERSITY OF COLORADO DENVER · PI CAMPBELL, THOMAS B. · 2007 to 2011
$8.3M
Colorado AIDS Clinical Trials UnitUM1AI069450 · NIAID · UNIVERSITY OF COLORADO DENVER · PI CAMPBELL, THOMAS B. · 2012 to 2013
$2.6M
Impact of Malnutrition on HIV Treatment Failure in Resource-Limited SettingsR01AI080417 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GUPTA, AMITA · 2009 to 2012
$2.3M
NIAID NIH HHS R01 AI080417NIAID NIH HHS U01 AI068634NIAID NIH HHS U01 AI068636NIAID NIH HHS U01 AI069450NIAID NIH HHS UM1 AI068636NIAID NIH HHS UM1 AI069450NIDA NIH HHS R01 DA016078
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antiretroviral therapyHIVIFN-γIL-18immune activationinflammasome

Identifiers

PMID27800521
PMCPMC5084713

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.