Evidence map›Paper›PMID 27800305›Full record

ArticleFrontiers in cellular and infection microbiology2016

Notch Signaling Contributes to Liver Inflammation by Regulation of Interleukin-22-Producing Cells in Hepatitis B Virus Infection.

Xin Wei, Jiu-Ping Wang, Chun-Qiu Hao, Xiao-Fei Yang, Lin-Xu Wang, Chang-Xing Huang, Xue-Fan Bai, Jian-Qi Lian, Ye Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Hepatocytes: A key role in liver inflammation.Frontiers in immunology · 2022
    Review
  6. Notch signaling pathway in infectious diseases: role in the regulation of immune response.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2021
    Review
  7. Article
  8. Review
  9. The Protective Roles of PPARα Activation in Triptolide-Induced Liver Injury.Toxicological sciences : an official journal of the Society of Toxicology · 2019
    Article
  10. [Interaction of notch signaling pathway with toll-like receptor 4 on the function of CD14+ monocytes in chronic hepatitis C patients].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2019
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xin WeiCenter for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University Xi'an, China.
Jiu-Ping WangDepartment of Infectious Diseases, Xijing Hospital, Fourth Military Medical University Xi'an, China.
Chun-Qiu HaoCenter for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University Xi'an, China.
Xiao-Fei YangCenter for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University Xi'an, China.
Lin-Xu WangCenter for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University Xi'an, China.
Chang-Xing HuangCenter for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University Xi'an, China.
Xue-Fan BaiCenter for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University Xi'an, China.
Jian-Qi LianCenter for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University Xi'an, China.
Ye ZhangCenter for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University Xi'an, China.
Air Force Medical University · CNXijing Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanism of hepatitis B virus (HBV) induced liver inflammation is not fully elucidated. Notch signaling augmented interleukin (IL)-22 secretion in CD4

Indexed as

Gene Expression RegulationSignal TransductionAnimalsCD4-Positive T-LymphocytesCells, CulturedHepatitis BHumansInterleukin-22InterleukinsKiller Cells, NaturalLiverMiceReceptor, Notch1Receptor, Notch2Interleukin-22InterleukinsReceptor, Notch1Receptor, Notch2hepatitis B virusinflammationinnate lymphoid cellsinterleukin-22Notch signaling

Identifiers

PMID27800305
PMCPMC5065963
OpenAlexW2529894222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.