ReviewPerioperative medicine (London, England)2016
Sarcopenia and sarcopenic obesity: do they predict inferior oncologic outcomes after gastrointestinal cancer surgery?
Review in Perioperative medicine (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Nutritional status and clinical outcomes in pediatric patients with solid tumors : A systematic review of the literature.Seminars in oncology · 2019Pooled it
- Trial
- Preoperative Skeletal Muscle Index as an Independent Predictor of Anastomotic Leakage After Colorectal Cancer Surgery: A Retrospective Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- CT-Derived Predictors of Incisional Hernia Following Colorectal Cancer Resection: A Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- Association of sarcopenia with the long-term risk of overall infections and infectious diseases: a prospective cohort study of 458 332 participants.MedScience · 2026Article
- The value of perioperative nutritional risk stratification in the prevention of surgical site infection: precision application from GLIM/PG-SGA to PNI, CONUT, and GNRI.Frontiers in nutrition · 2026Review
- Article
- Evaluation of preoperative visceral fat area / psoas muscle area ratio and prognosis in patients with colorectal cancer.Annals of gastroenterological surgery · 2025Article
- The effects of sarcopenic obesity on immediate postoperative outcomes after pancreatoduodenectomy: a retrospective cohort study.Annals of surgical treatment and research · 2024Article
- Sarcopenic obesity in cancer.Radiology and oncology · 2024Review
- Larger Remaining Stomach Volume Is Associated With Better Nutrition and Muscle Preservation in Patients With Gastric Cancer Receiving Distal Gastrectomy With Gastroduodenostomy.Journal of gastric cancer · 2022Article
- Article
- Prognostic value and association of sarcopenic obesity and systemic inflammatory indexes in patients with hepatocellular carcinoma following hepatectomy and the establishment of novel predictive nomograms.Journal of gastrointestinal oncology · 2021Article
- Assessment of body composition and association with clinical outcomes in patients with lung and colorectal cancer.BJR open · 2021Article
- Skeletal muscle and adipose tissue changes in the first phase of treatment of pediatric solid tumors.Cancer medicine · 2021Article
- Skeletal Muscle Mass Loss During Cancer Treatment: Differences by Race and Cancer Site.Oncology nursing forum · 2020Article
- Prognostic role of pre-sarcopenia and body composition with long-term outcomes in obstructive colorectal cancer: a retrospective cohort study.World journal of surgical oncology · 2020Article
- Prognostic Impact of Sarcopenia and Skeletal Muscle Loss During Neoadjuvant Chemoradiotherapy in Esophageal Cancer.Cancers · 2020Article
- Single-slice CT measurements allow for accurate assessment of sarcopenia and body composition.European radiology · 2020Article
- Sarcopenic Obesity: Epidemiologic Evidence, Pathophysiology, and Therapeutic Perspectives.Current obesity reports · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Sarcopenia, or loss of skeletal muscle mass and quality, has been studied as part of aging and adverse health outcomes in elderly patients but has only recently been evaluated as a separate condition in cancer patients and important indicator of adverse outcomes. Currently, its definition and method of assessment are still being debated. Sarcopenia within an increasingly obese population has led to a subgroup with sarcopenic obesity, at even higher risk of adverse outcomes. Yet, sarcopenia often goes undiagnosed in these patients, hidden beneath higher body mass index. Identifying sarcopenic and sarcopenic obese subpopulations would allow for more effective treatment plans and potential avoidance of suboptimal outcomes, as well as the chance to intervene and combat these modifiable risk factors. This review will examine available literature on the definition and methods of evaluating sarcopenia and sarcopenic obesity, summarize the effectiveness of sarcopenia and sarcopenic obesity as predictors of outcomes after gastrointestinal cancer surgery, including colorectal cancer resection, liver resection, and pancreatic resection, and outline strategies to minimize the impact of sarcopenia. It is clear that untreated sarcopenia and sarcopenic obesity can be associated with suboptimal post-operative outcomes, especially infections and disease-free or overall survival.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.