Evidence map›Paper›PMID 27799911›Full record

ArticleFrontiers in pharmacology2016

Huperzine A Provides Robust and Sustained Protection against Induced Seizures in

Jennifer C Wong, Stacey B B Dutton, Stephen D Collins, Steven Schachter, Andrew Escayg

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
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  12. Targeted Molecular Strategies for Genetic Neurodevelopmental Disorders: Emerging Lessons from Dravet Syndrome.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2023
    Review
  13. Article
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  16. Review
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  19. Autistic-like behavior, spontaneous seizures, and increased neuronal excitability in a Scn8a mouse model.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jennifer C WongDepartment of Human Genetics, Emory University Atlanta, GA, USA.
Stacey B B DuttonDepartment of Human Genetics, Emory UniversityAtlanta, GA, USA; Department of Biology, Agnes Scott CollegeAtlanta, GA, USA.
Stephen D CollinsBiscayne Pharmaceuticals Miami, FL, USA.
Steven SchachterDepartment of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, and Massachusetts General Hospital Boston, MA, USA.
Andrew EscaygDepartment of Human Genetics, Emory University Atlanta, GA, USA.
Emory University · USMassachusetts General Hospital · USSt. Thomas University · US

Funding

Understanding the role of sodium channels in epilepsyR01NS072221 · NINDS · EMORY UNIVERSITY · PI ESCAYG, ANDREW P · 2011 to 2014
$1.3M
Towards the development of an effective treatment for SCN1A-derived epilepsyR21NS098776 · NINDS · EMORY UNIVERSITY · PI ESCAYG, ANDREW P · 2016 to 2017
$426k
NINDS NIH HHS R01 NS072221NINDS NIH HHS R21 NS098776
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dravet syndromegenetic epilepsy with febrile seizures plushuperzine AScn1aseizure

Identifiers

PMID27799911
PMCPMC5065986
OpenAlexW2530807081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.