Evidence map›Paper›PMID 27799897›Full record

ArticleFrontiers in cellular neuroscience2016

Enhancement of Peripheral Nerve Regrowth by the Purine Nucleoside Analog and Cell Cycle Inhibitor, Roscovitine.

Vincent Law, Sophie Dong, Jesusa L Rosales, Myung-Yung Jeong, Douglas Zochodne, Ki-Young Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Vincent LawDepartment of Cell Biology and Anatomy, Arnie Charbonneau Cancer Institute, Hotchkiss Brain Institute, University of Calgary Calgary, AB, Canada.
Sophie DongDepartment of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary Calgary, AB, Canada.
Jesusa L RosalesDepartment of Biochemistry and Molecular Biology, Snyder Institute for Chronic Diseases, University of Calgary Calgary, AB, Canada.
Myung-Yung JeongDepartment of Cogno-Mechatronics Engineering, Pusan National University Pusan, South Korea.
Douglas ZochodneDepartment of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary Calgary, AB, Canada.
Ki-Young LeeDepartment of Cell Biology and Anatomy, Arnie Charbonneau Cancer Institute, Hotchkiss Brain Institute, University of Calgary Calgary, AB, Canada.
University of Calgary · CAAllen Institute for Brain Science · USPusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral nerve regeneration is a slow process that can be associated with limited outcomes and thus a search for novel and effective therapy for peripheral nerve injury and disease is crucial. Here, we found that roscovitine, a synthetic purine nucleoside analog, enhances neurite outgrowth in neuronal-like PC12 cells. Furthermore,

Indexed as

axoncytoskeletoninjuryperipheral nerveregeneration

Identifiers

PMID27799897
PMCPMC5066473
OpenAlexW2534063977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.