Evidence map›Paper›PMID 27799809›Full record

ReviewJournal of inflammation research2016

Insights into the molecular etiology of exercise-induced inflammation: opportunities for optimizing performance.

Ioannis G Fatouros, Athanasios Z Jamurtas

2 registry-linked trialsOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of inflammation research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 77 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 6 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05044936 early_phase1withdrawnnot on this mapstarted 2023, after this paper: background citation

The Effects of Topical Cannabidiol Cream on Post-exercise Recovery

TypeinterventionalSponsorUniversity of New MexicoRan2023 to 2023Enrolled0ConditionsMuscle DamageArmsCannabidiol Oil, Resistance Exercise
NCT07728422 nacompletednot on this mapstarted 2024, after this paper: background citation

Effects of Ozone Therapy Modalities on Biochemical Markers of Muscle Damage Following Eccentric Exercise

TypeinterventionalSponsorInonu UniversityRan2024 to 2025Enrolled32ConditionsOzone Therapy, Muscle Damage, Oxidative Stress, RecoveryArmsAutohemotherapy, Ozone Sauna Therapy, Ozonated Lavender Oil Massage
3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 6 syntheses or guidelines pooled it, 130 citations in OpenAlex.

  1. Pooled it
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  7. Trial
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  9. Efficacy ofNutrients · 2024
    Trial
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  15. Effect ofNutrients · 2019
    Trial
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  19. Eccentric Exercise and Muscle Damage: An Introductory Guide.Journal of functional morphology and kinesiology · 2026
    Review
  20. Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ioannis G FatourosSchool of Physical Education and Sport Sciences, University of Thessaly, Karies, Trikala, Greece.
Athanasios Z JamurtasSchool of Physical Education and Sport Sciences, University of Thessaly, Karies, Trikala, Greece.
University of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study of exercise-induced muscle damage (EIMD) is of paramount importance not only because it affects athletic performance but also because it is an excellent model to study the mechanisms governing muscle cachexia under various clinical conditions. Although, a large number of studies have investigated EIMD and its associated inflammatory response, several aspects of skeletal muscles responses remain unclear. In the first section of this article, the mechanisms of EIMD are reviewed in an attempt to follow the events that result in functional and structural alterations of skeletal muscle. In the second section, the inflammatory response associated with EIMD is presented with emphasis in leukocyte accumulation through mechanisms that are largely coordinated by pro- and anti-inflammatory cytokines released either by injured muscle itself or other cells. The practical applications of EIMD and the subsequent inflammatory response are discussed with respect to athletic performance. Specifically, the mechanisms leading to performance deterioration and development of muscle soreness are discussed. Emphasis is given to the factors affecting individual responses to EIMD and the resulting interindividual variability to this phenomenon.

Indexed as

aseptic inflammationexerciseimmune systemmuscle damagerecoveryredox status

Identifiers

PMID27799809
PMCPMC5085309
OpenAlexW2537808248

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.