Evidence map›Paper›PMID 27799807›Full record

ArticleClinical, cosmetic and investigational dermatology2016

Safety and performance of cohesive polydensified matrix hyaluronic acid fillers with lidocaine in the clinical setting - an open-label, multicenter study.

Ulrich Kühne, Jørgen Esmann, Dennis von Heimburg, Matthias Imhof, Petra Weissenberger, Gerhard Sattler

8 registry-linked trialsAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03537456 nacompletednot on this mapstarted 2018, after this paper: background citation

A Multicentre, Open-label, Interventional, Pilot Trial to Assess the Performance and Tolerance of mRDX-02-17 Dermal Filler in the Facial Rejuvenation

TypeinterventionalSponsorMesoestetic Pharma Group S.L.Ran2018 to 2019Enrolled39ConditionsFacial RejuvenationArmsmRDX-02-17
NCT04101825 nacompletednot on this mapstarted 2020, after this paper: background citation

Open, Non-comparative Study to Evaluate the Performance and Safety of the Medical Device AURALYA® (Hyaluronic Acid-dermal Filler) in the Treatment of Nasolabial Wrinkles to Obtain Facial Rejuvenation

TypeinterventionalSponsorI.R.A. Istituto Ricerche Applicate S.p.A.Ran2020 to 2021Enrolled60ConditionsNasolabial Fold, HypoplasticArmsAuralya
NCT04103125 nacompletednot on this mapstarted 2020, after this paper: background citation

Open, Non-Comparative Study To Evaluate The Performance And Safety Of The Medical Device JANESSE® (Hyaluronic Acid-Dermal Filler) In The Correction Of Facial Wrinkles

TypeinterventionalSponsorI.R.A. Istituto Ricerche Applicate S.p.A.Ran2020 to 2020Enrolled61ConditionsWrinkleArmsJanesse® is a sterile, injectable, non-pyrogenic, re-absorbable medical product made of reticulated hyaluronic acid of non-animal origin, produced via bacterial fermentation.
NCT04103918 nacompletednot on this mapstarted 2020, after this paper: background citation

Open, Non-Comparative Study To Evaluate The Performance And Safety Of The Medical Device Jalucomplex® (Hyaluronic Acid-Dermal Filler) In the Treatment Of Facial And Neck Wrinkles To Obtain Facial Rejuvanation

TypeinterventionalSponsorI.R.A. Istituto Ricerche Applicate S.p.A.Ran2020 to 2021Enrolled60ConditionsWrinkleArmsJalucomplex
NCT05239117 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Open, Non-comparative, Multicentre Clinical Investigation to Evaluate the Performance and Safety of the Medical Device Plenhyage® (Polymerised Polynucleotides Dermal Filler) in the Treatment of Dermal Tissue Defects

TypeinterventionalSponsorI.R.A. Istituto Ricerche Applicate S.p.A.Ran2022 to 2022Enrolled48ConditionsCicatrix, Lipodystrophy, PlaqueArmsPlenhyage
NCT05239130 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Open, Non-comparative, Multicentre Clinical Investigation to Evaluate the Performance and Safety of the Medical Device Auralya® (Hyaluronic Acid-dermal Filler) in the Treatment of Facial Dermal Tissue Defects

TypeinterventionalSponsorI.R.A. Istituto Ricerche Applicate S.p.A.Ran2022 to 2022Enrolled48ConditionsCicatrix, Lipodystrophy, PlaqueArmsAuralya
NCT05239156 nacompletednot on this mapstarted 2022, after this paper: background citation

Open, Non-comparative, Multicentre Clinical Investigation to Evaluate the Performance and Safety of the Medical Device Janesse® (Hyaluronic Acid-dermal Filler) in the Treatment of Facial Dermal Tissue Defects

TypeinterventionalSponsorI.R.A. Istituto Ricerche Applicate S.p.A.Ran2022 to 2022Enrolled48ConditionsCicatrix, Lipodystrophy, PlaqueArmsJanesse
NCT05239351 nacompletednot on this mapstarted 2022, after this paper: background citation

Open, Non-comparative, Multicentre Clinical Investigation to Evaluate the Performance and Safety of the Medical Device Jalucomplex® (Hyaluronic Acid-dermal Filler) in the Treatment of Facial and Neck Dermal Tissue Defects

TypeinterventionalSponsorI.R.A. Istituto Ricerche Applicate S.p.A.Ran2022 to 2022Enrolled48ConditionsCicatrix, Lipodystrophy, PlaqueArmsJalucomplex
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Cohesive Polydensified MatrixClinical, cosmetic and investigational dermatology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ulrich KühneAesthetische Dermatologie im Medico Palais, Bad Soden, Germany.
Jørgen EsmannJørgen Esmann Aps, Hellerup, Denmark.
Dennis von HeimburgPraxisklinik Kaiserplatz, Frankfurt am Main, Germany.
Matthias ImhofAesthetische Dermatologie im Medico Palais, Bad Soden, Germany.
Petra WeissenbergerCorporate Clinical Research, Merz Pharmaceuticals GmbH, Frankfurt am Main, Germany.
Gerhard SattlerRosenparkklinik GmbH, Darmstadt, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cohesive polydensified matrix (CPM

Indexed as

Beloterocohesive polydensified matrixdermal fillersEsthélisFortélisModélis

Identifiers

PMID27799807
PMCPMC5076541

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.