Evidence map›Paper›PMID 27799753›Full record

ReviewClinical interventions in aging2016

Mutations, associated with early-onset Alzheimer's disease, discovered in Asian countries.

Eva Bagyinszky, Young Chul Youn, Seong Soo A An, SangYun Kim

Open access · goldAbstract readReview
In one paragraph

Review in Clinical interventions in aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. The genetic landscape of early-onset Alzheimer's disease in China.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. PathogenicDiagnostics (Basel, Switzerland) · 2020
    Article
  14. The Genetics of Alzheimer's Disease in the Chinese Population.International journal of molecular sciences · 2020
    Review
  15. Article
  16. Article
  17. International journal of molecular sciences · 2019
    Article
  18. Two Novel Mutations and aAging and disease · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Eva BagyinszkyDepartment of BioNano Technology, Gachon University, Gyeonggi-do.
Young Chul YounDepartment of Neurology, College of Medicine, Chung-Ang University, Seoul.
Seong Soo A AnDepartment of BioNano Technology, Gachon University, Gyeonggi-do.
SangYun KimDepartment of Neurology, Seoul National University Budang Hospital, Gyeonggi-do, South Korea.
Gachon University · KRChung-Ang University · KRSeoul National University Bundang Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD), the most common form of senile dementia, is a genetically complex disorder. In most Asian countries, the population and the number of AD patients are growing rapidly, and the genetics of AD has been extensively studied, except in Japan. However, recent studies have been started to investigate the genes and mutations associated with AD in Korea, the People's Republic of China, and Malaysia. This review describes all of the known mutations in three early-onset AD (EOAD) causative genes (

Indexed as

Alzheimer DiseaseAmyloid beta-Protein PrecursorAsiaAsian PeopleGenetic TestingGenome-Wide Association StudyHumansMutationPresenilin-1Presenilin-2Amyloid beta-Protein PrecursorAPP protein, humanPresenilin-1Presenilin-2PSEN1 protein, humanPSEN2 protein, humanamyloid precursor proteinAsiageneticsmutationpresenilin

Identifiers

PMID27799753
PMCPMC5074729
OpenAlexW2536988631

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.