Evidence map›Paper›PMID 27799620›Full record

ArticleThe Journal of experimental medicine2016

MAIT cells promote inflammatory monocyte differentiation into dendritic cells during pulmonary intracellular infection.

Anda I Meierovics, Siobhán C Cowley

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of experimental medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05598346 (Significance and Biological Importance of Mucosal Associated Invariant T Cells in Inflammatory Bowel Disease Patients), which is not on this map. Cited by 93 papers.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05598346 unknown statusnot on this mapstarted 2023, after this paper: background citation

Significance and Biological Importance of Mucosal Associated Invariant T Cells in Inflammatory Bowel Disease Patients

TypeobservationalSponsorAssiut UniversityRan2023 to 2024Enrolled70ConditionsInflammatory Bowel Diseases
3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 153 citations in OpenAlex.

  1. Trial
  2. Review
  3. Gut archaea drive human MAIT cell responses.bioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Human MAIT cell response profiles biased toward IL-17 or IL-10 are distinct effector states directed by the cytokine milieu.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Review
  10. MAIT cells modulating the oral lichen planus immune microenvironment: a cellular crosstalk perspective.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
  11. Bacterial and host interactions inFrontiers in microbiology · 2025
    Review
  12. Review
  13. The immune response toFrontiers in microbiology · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. MAIT Cells Modulate Innate Immune Cells and Inhibit Colon Cancer Growth.bioRxiv : the preprint server for biology · 2024
    Article
  18. Article
  19. Article
  20. Review

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anda I MeierovicsLaboratory of Mucosal Pathogens and Cellular Immunology, Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993.
Siobhán C CowleyLaboratory of Mucosal Pathogens and Cellular Immunology, Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993 siobhan.cowley@fda.hhs.gov.ORCID 0000-0003-3073-0269
Center for Biologics Evaluation and Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucosa-associated invariant T (MAIT) cells are a unique innate T cell subset that is necessary for rapid recruitment of activated CD4

Indexed as

Cell DifferentiationAdoptive TransferAnimalsBone MarrowCD11b AntigenCD4-Positive T-LymphocytesCytokinesDendritic CellsFemaleFrancisella tularensisGranulocyte-Macrophage Colony-Stimulating FactorHistocompatibility Antigens Class IIntracellular SpaceLungLung DiseasesMaleCcr2 protein, mouseCD11b AntigenCytokinesGranulocyte-Macrophage Colony-Stimulating FactorHistocompatibility Antigens Class IReceptors, CCR2Recombinant ProteinsVaccines

Identifiers

PMID27799620
PMCPMC5110023
OpenAlexW2545982909

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.