ArticleProceedings of the National Academy of Sciences of the United States of America2016
Precise gene editing paves the way for derivation of Mannheimia haemolytica leukotoxin-resistant cattle.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 53 citations in OpenAlex.
- Insights from adaptive immune regulation for disease resistance breeding in livestock and poultry.Science China. Life sciences · 2026Review
- Retrospect and prospect: reproductive technologies in beef cattle.Molecular biology reports · 2025Review
- Commercial perspectives: Genome editing as a breeding tool for health and well-being in dairy cattle.JDS communications · 2024Article
- Genome editing: An insight into disease resistance, production efficiency, and biomedical applications in livestock.Functional & integrative genomics · 2024Review
- Versatile generation of precise gene edits in bovines using SEGCPN.BMC biology · 2023Article
- Application of Gene Editing Technology in Resistance Breeding of Livestock.Life (Basel, Switzerland) · 2022Review
- Enhancing Animal Disease Resistance, Production Efficiency, and Welfare through Precise Genome Editing.International journal of molecular sciences · 2022Review
- Potentials, prospects and applications of genome editing technologies in livestock production.Saudi journal of biological sciences · 2022Review
- Review
- CRISPR, animals, and FDA oversight: Building a path to success.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- One-Step Homology Mediated CRISPR-Cas Editing in Zygotes for Generating Genome Edited Cattle.The CRISPR journal · 2020Article
- Improvement of Disease Resistance in Livestock: Application of Immunogenomics and CRISPR/Cas9 Technology.Animals : an open access journal from MDPI · 2020Review
- Review
- Review
- Application of genome editing in farm animals: cattle.Transgenic research · 2019Article
- Livestock 2.0 - genome editing for fitter, healthier, and more productive farmed animals.Genome biology · 2018Review
- A bovine CD18 signal peptide variant with increased binding activity toF1000Research · 2018Article
- HMEJ-based safe-harbor genome editing enables efficient generation of cattle with increased resistance to tuberculosis.The Journal of biological chemistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Signal peptides of membrane proteins are cleaved by signal peptidase once the nascent proteins reach the endoplasmic reticulum. Previously, we reported that, contrary to the paradigm, the signal peptide of ruminant CD18, the β subunit of β
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.