ArticleThe Journal of cell biology2016
Msi RNA-binding proteins control reserve intestinal stem cell quiescence.
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Article in The Journal of cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 70 citations in OpenAlex.
- Building and regenerating intestines by manipulating intestinal stem cells.Nature reviews. Gastroenterology & hepatology · 2026Review
- RNA binding protein Musashi1 interacts with the viral genomic RNA and restricts SARS-CoV-2 infection by repressing translation.Nucleic acids research · 2026Article
- Metabolic regulation of intestinal homeostasis: molecular and cellular mechanisms and diseases.MedComm · 2024Review
- Article
- Subepithelial Stromal Cells: Their Roles and Interactions with Intestinal Epithelial Cells during Gut Mucosal Homeostasis and Regeneration.Biomedicines · 2024Review
- p53 suppresses MHC class II presentation by intestinal epithelium to protect against radiation-induced gastrointestinal syndrome.Nature communications · 2024Article
- Single-cell mapping identifies MSICancer cell · 2023Article
- TGFB1 induces fetal reprogramming and enhances intestinal regeneration.Cell stem cell · 2023Article
- Article
- Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity.iScience · 2023Article
- Spatial transcriptomics add a new dimension to our understanding of the gut.American journal of physiology. Gastrointestinal and liver physiology · 2023Review
- TGFB1 Induces Fetal Reprogramming and Enhances Intestinal Regeneration.bioRxiv : the preprint server for biology · 2023Article
- MiMIC analysis reveals an isoform specific role for Drosophila Musashi in follicle stem cell maintenance and escort cell function.Cell death discovery · 2022Article
- Autophagic state prospectively identifies facultative stem cells in the intestinal epithelium.EMBO reports · 2022Article
- Thyroid hormone signaling in the intestinal stem cells and their niche.Cellular and molecular life sciences : CMLS · 2022Review
- Mechanisms modulating the activities of intestinal stem cells upon radiation or chemical agent exposure.Journal of radiation research · 2022Article
- MSI2 deficiency in ILC3s attenuates DSS-induced colitis by affecting the intestinal microbiota.Frontiers in immunology · 2022Article
- The RNA-Binding Protein Musashi1 Regulates a Network of Cell Cycle Genes in Group 4 Medulloblastoma.Cells · 2021Article
- Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas.Science advances · 2021Article
- Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Maryam YousefiDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Ning LiDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Angela Nakauka-DdambaDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.ORCID http://orcid.org/0000-0002-4631-7105
Shan WangDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.ORCID http://orcid.org/0000-0002-0429-8890
Kimberly DavidowDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.ORCID http://orcid.org/0000-0003-0597-5475
Jenna SchoenbergerDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.ORCID http://orcid.org/0000-0003-4278-669X
Zhengquan YuState Key Laboratories for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing 100083, China.ORCID http://orcid.org/0000-0001-8696-2013
Shane T JensenDepartment of Biostatistics, the Wharton School, University of Pennsylvania, Philadelphia, PA 19104.
Michael G KharasMolecular Pharmacology and Chemistry Program, Experimental Therapeutics Center and Center for Stem Cell Biology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065.ORCID http://orcid.org/0000-0002-1165-6991
Christopher J LengnerDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104 lengner@vet.upenn.edu.ORCID http://orcid.org/0000-0002-0574-5189
University of Pennsylvania · USChina Agricultural University · CNCalifornia Institute for Regenerative Medicine · USMemorial Sloan Kettering Cancer Center · US
Funding
Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4MTRANSGENIC AND CHIMERIC MOUSE COREP30DK050306 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI REBECCA G WELLS · 1997 to 2026
$32.5MUncovering the role for MSI2 network in hematopoietic stem cellsR01DK101989 · NIDDK · SLOAN-KETTERING INST CAN RESEARCH · PI Michael Kharas, Vijay Ganesh Sankaran · 2014 to 2026
$6.2MCharacterizing the MSI2 network in leukemiaR01CA193842 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI KHARAS, MICHAEL · 2015 to 2025
$4.1MDeregulation of MSI RNA-binding proteins promotes intestinal tumorigenesisR01CA168654 · NCI · UNIVERSITY OF PENNSYLVANIA · PI LENGNER, CHRISTOPHER JOACHIM · 2012 to 2021
$3.7MThe basis for and function of enteroendocrine lineage plasticity in the intestinal DNA damage responseR01DK106309 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI LENGNER, CHRISTOPHER JOACHIM · 2016 to 2023
$3.3MNCI NIH HHS P30 CA015704NCI NIH HHS R01 CA168654NCI NIH HHS R01 CA193842NIDDK NIH HHS P30 DK050306NIDDK NIH HHS R01 DK101989NIDDK NIH HHS R01 DK106309
Abstract
Regeneration of the intestinal epithelium is driven by multiple intestinal stem cell (ISC) types, including an active, radiosensitive Wnt
Indexed as
AnimalsCell LineageCell ProliferationEpitheliumGamma RaysHomeostasisIntestinesMice, Inbred C57BLNerve Tissue ProteinsRadiation InjuriesResting Phase, Cell CycleRNA-Binding ProteinsS PhaseStem CellsUp-RegulationWnt Signaling PathwayMsi1h protein, mouseMsi2h protein, mouseNerve Tissue ProteinsRNA-Binding Proteins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.