Evidence map›Paper›PMID 27799287›Full record

ArticleEMBO reports2017

CD1d-mediated activation of group 3 innate lymphoid cells drives IL-22 production.

Julia Saez de Guinoa, Rebeca Jimeno, Nazanin Farhadi, Peter J Jervis, Liam R Cox, Gurdyal S Besra, Patricia Barral

Open access · hybridAbstract read
In one paragraph

Article in EMBO reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. ILC3: a case of conflicted identity.Frontiers in immunology · 2023
    Review
  9. Review
  10. Article
  11. Article
  12. Non-zero-sum microbiome immune system interactions.European journal of immunology · 2021
    Review
  13. Article
  14. CD1dFrontiers in immunology · 2021
    Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Julia Saez de GuinoaThe Peter Gorer Department of Immunobiology, King's College London, London, UK.
Rebeca JimenoThe Peter Gorer Department of Immunobiology, King's College London, London, UK.
Nazanin FarhadiThe Peter Gorer Department of Immunobiology, King's College London, London, UK.
Peter J JervisSchool of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK.
Liam R CoxSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, UK.ORCID 0000-0001-7018-3904
Gurdyal S BesraSchool of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK.
Patricia BarralThe Peter Gorer Department of Immunobiology, King's College London, London, UK patricia.barral@kcl.ac.uk.
King's College London · GBUniversity of Birmingham · GB

Funding

Medical Research Council G1001750Medical Research Council MR/L008157/1NIAID NIH HHS HHSN272201300006C
6 · The paper itself

Abstract

Innate lymphoid cells (ILCs) are a heterogeneous family of immune cells that play a critical role in a variety of immune processes including host defence against infection, wound healing and tissue repair. Whether these cells are involved in lipid-dependent immunity remains unexplored. Here we show that murine ILCs from a variety of tissues express the lipid-presenting molecule CD1d, with group 3 ILCs (ILC3s) showing the highest level of expression. Within the ILC3 family, natural cytotoxicity triggering receptor (NCR)

Indexed as

Immunity, InnateLymphocyte ActivationAnimalsAntigen PresentationAntigens, CD1dBiomarkersGene ExpressionImmunophenotypingInterleukin-22InterleukinsLipid MetabolismLipidsLymphocytesLymphocyte SubsetsMiceMice, TransgenicAntigens, CD1dBiomarkersInterleukin-22InterleukinsLipidsCD1dIL‐22ILCNKT cell

Identifiers

PMID27799287
PMCPMC5210076
OpenAlexW2544747409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.