ArticleCirculation2016
Citizen Petition to the US Food and Drug Administration to Change Prescribing Guidelines: The Metformin Experience.
Abstract read
In one paragraph
Article in Circulation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Baseline Characteristics and Patient-Reported Outcomes of ADPKD Patients in the Multicenter TAME-PKD Clinical Trial.Kidney360 · 2020Trial
- Large Language Model GPT-4 Compared to Endocrinologist Responses on Initial Choice of Glucose-Lowering Medication Under Conditions of Clinical Uncertainty.Diabetes care · 2025Article
- Prescriber Uncertainty as Opportunity to Improve Care of Type 2 Diabetes with Chronic Kidney Disease: Mixed Methods Study.Journal of general internal medicine · 2023Article
- Transition Metal-Decorated MgACS omega · 2023Article
- Translating Research into Health Policy: The Citizen Petition Experience with the Food and Drug Administration.Cancer treatment and research · 2022Article
- Rates of Metformin Use in Stage 3b Chronic Kidney Disease Rose After FDA Label Change.Journal of general internal medicine · 2021Article
- Should metformin remain the first-line therapy for treatment of type 2 diabetes?Therapeutic advances in endocrinology and metabolism · 2021Review
- Lactic acidosis incidence with metformin in patients with type 2 diabetes and chronic kidney disease: A retrospective nested case-control study.Endocrinology, diabetes & metabolism · 2021Article
- Where Does Metformin Stand in Modern Day Management of Type 2 Diabetes?Pharmaceuticals (Basel, Switzerland) · 2020Review
- The FDA Metformin Label Change and Racial and Sex Disparities in Metformin Prescription among Patients with CKD.Journal of the American Society of Nephrology : JASN · 2020Article
- Challenges and Strategies for Inpatient Diabetes Management in Older Adults.Diabetes spectrum : a publication of the American Diabetes Association · 2020Article
- Reports of Lactic Acidosis Attributed to Metformin, 2015-2018.Diabetes care · 2020Article
- Differences in National Diabetes Treatment Patterns and Trends between Older and Younger Adults.Journal of the American Geriatrics Society · 2019Article
- Changes in metformin use and other antihyperglycemic therapies after insulin initiation in patients with type 2 diabetes.Diabetes research and clinical practice · 2018Article
- Metformin: clinical use in type 2 diabetes.Diabetologia · 2017Review
- Metformin Use in Patients With Historical Contraindications.Annals of internal medicine · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Kasia J LipskaFrom Section of Endocrinology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT (K.J.L., S.E.I.); Department of Healthcare Policy and Research, Weill Cornell Medical College and Memorial Sloan Kettering Cancer Center, New York, NY (J.H.F.); and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (S.H.). kasia.lipska@yale.edu.
James H FloryFrom Section of Endocrinology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT (K.J.L., S.E.I.); Department of Healthcare Policy and Research, Weill Cornell Medical College and Memorial Sloan Kettering Cancer Center, New York, NY (J.H.F.); and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (S.H.).
Sean HennessyFrom Section of Endocrinology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT (K.J.L., S.E.I.); Department of Healthcare Policy and Research, Weill Cornell Medical College and Memorial Sloan Kettering Cancer Center, New York, NY (J.H.F.); and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (S.H.).
Silvio E InzucchiFrom Section of Endocrinology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT (K.J.L., S.E.I.); Department of Healthcare Policy and Research, Weill Cornell Medical College and Memorial Sloan Kettering Cancer Center, New York, NY (J.H.F.); and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (S.H.).
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MYale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Denise Esserman · 2002 to 2026
$37.9MPredicting Severe Hypoglycemia among Older Adults with DiabetesK23AG048359 · NIA · YALE UNIVERSITY · PI LIPSKA, KASIA JOANNA · 2014 to 2018
$778kImproving Metformin Utilization And Diabetes Control Through Patient-Centered Outcomes ResearchK08HS023898 · AHRQ · WEILL MEDICAL COLL OF CORNELL UNIV · PI FLORY, JAMES H · 2015 to 2019
$760kAHRQ HHS K08 HS023898NCATS NIH HHS UL1 TR001863NIA NIH HHS K23 AG048359NIA NIH HHS L30 AG045923NIA NIH HHS P30 AG021342
Abstract
PubMed holds no abstract for this paper.
Indexed as
Drug LabelingLegislation, DrugMetforminUnited States Food and Drug AdministrationDiabetes Mellitus, Type 2Drug PrescriptionsHumansPractice Guidelines as TopicUnited StatesMetformindiabetes mellituskidneylactate
Identifiers
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.