Evidence map›Paper›PMID 27798772›Full record

ArticleAdvances in therapy2017

Awareness, Knowledge, and Perceptions of Biosimilars Among Specialty Physicians.

Hillel Cohen, Donna Beydoun, David Chien, Tracy Lessor, Dorothy McCabe, Michael Muenzberg, Robert Popovian, Jonathan Uy

Abstract readComparative Study
In one paragraph

Article in Advances in therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Biosimilar monoclonal antibodies for cancer treatment in adults.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Perceptions and Preferences for Defining Biosimilar Products in Prescription Drug Promotion.Journal of the American Board of Family Medicine : JABFM · 2025
    Trial
  8. Trial
  9. Article
  10. Article
  11. Article
  12. Review
  13. Evaluation of rheumatologists' knowledge of biosimilars.Advances in rheumatology (London, England) · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Unveiling the Biosimilar Paradox of Oncologists' Perceptions and Hesitations in South Korea: A Web-Based Survey Study.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2024
    Article

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hillel CohenSandoz Inc., Princeton, NJ, USA. hillel.cohen@sandoz.com.
Donna BeydounMerck & Co., Inc., Kenilworth, NJ, USA.
David ChienAmgen, Thousand Oaks, CA, USA.
Tracy LessorFeinstein Kean Healthcare, New York, NY, USA.
Dorothy McCabeBoehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA.
Michael MuenzbergAres Trading SA, Aubonne, Switzerland.
Robert PopovianPfizer Inc., New York, NY, USA.
Jonathan UySandoz Inc., Princeton, NJ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Biosimilars Forum conducted a survey through an independent organization from November 20, 2015 to January 4, 2016 in order to assess current levels of awareness, knowledge, and perceptions of biosimilars among US specialty physicians who already prescribe biologics. The survey was intended to provide a baseline level of knowledge about biosimilars and will be repeated in 2-3 years in order to monitor trends over time.

methodsA 19-question survey was created by the Biosimilars Forum and was administered by an independent third party.

resultsResponses were obtained from 1201 US physicians across specialties that are high prescribers of biologics, including dermatologists, gastroenterologists, hematologist-oncologists, medical oncologists, nephrologists, and rheumatologists.

conclusionsThe results of this survey highlight a significant need for evidence-based education about biosimilars for physicians across specialties. Five major knowledge gaps were identified: defining biologics, biosimilars, and biosimilarity; understanding the approval process and the use of "totality of evidence" to evaluate biosimilars; understanding that the safety and immunogenicity of a biosimilar are comparable to the originator biologic; understanding the rationale for extrapolation of indications; and defining interchangeability and the related rules regarding pharmacy-level substitution.

fundingBiosimilars Forum.

Indexed as

Health Knowledge, Attitudes, PracticeAdultAttitude of Health PersonnelBiosimilar PharmaceuticalsDrug-Related Side Effects and Adverse ReactionsFemaleHumansMaleMiddle AgedPhysiciansSurveys and QuestionnairesUnited StatesBiosimilar PharmaceuticalsBiologicBiosimilarBiosimilarityExtrapolationImmunogenicityInterchangeabilityOriginator biologic

Identifiers

PMID27798772
PMCPMC5126187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.