ReviewDrugs & aging2016
Practical Management of Anaesthesia in the Elderly.
Review in Drugs & aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Comparing the Effect of Spinal and General Anesthesia for Hip Fracture Surgery in Older Patients: A Meta-analysis of Randomized Clinical Trials.Orthopaedic surgery · 2023Pooled it
- Trial
- Effect of creatine phosphate sodium on bispectral index and recovery quality during the general anaesthesia emergence period in elderly patients: A randomized, double-blind, placebo-controlled trial.The Journal of international medical research · 2018Trial
- Article
- Does supine versus lateral position affect operative time and reduction quality for elderly intertrochanteric femur fractures?European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- From pharmacokinetics to precision dosing: optimizing continuous infusion regimens of ciprofol for elderly patients.Frontiers in pharmacology · 2026Article
- Remimazolam in elderly patients undergoing EBUS-TBNA: protocol for a randomized clinical trial.International journal of surgery protocols · 2025Article
- What Do Patients Know About Anesthesia and Anesthesiologists?Journal of clinical medicine · 2025Review
- Anesthesia Considerations in Older Adults Undergoing Emergency Mechanical Thrombectomy for Acute Ischaemic Stroke.Drugs & aging · 2025Review
- Reliability of nociceptive monitors vs. standard practice during general anesthesia: a prospective observational study.BMC anesthesiology · 2025Observational
- Comparative study of the pharmacokinetics, efficacy and safety of ET-26 in elderly and non-elderly subjects: the results of a phase I clinical trial.Frontiers in pharmacology · 2025Article
- Use of Neuromuscular Blocking Agents in Elderly Patients: A Narrative Review in Geriatric Medicine.International journal of general medicine · 2025Review
- Determining the Median Effective Dose of Remimazolam for Anesthesia Induction in Patients Undergoing Endoscopic Retrograde Cholangiopancreatography: An Age-Stratified Study.Drug design, development and therapy · 2025Article
- Considerations for Anesthesia in Older Adults with Cannabis Use.Drugs & aging · 2024Review
- Vestibular schwannoma surgery in the ninth decade of life: a case series.Acta neurochirurgica · 2024Observational
- Article
- Free Flap Reconstruction of the Extremities in Patients Who are ≥65 Years Old: A Single-Center Retrospective 1-to-1 Matched Analysis.Clinical interventions in aging · 2021Article
- Management of Ambulatory Anesthesia in Older Adults.Drugs & aging · 2020Review
- Anesthetic management of geriatric patients.Korean journal of anesthesiology · 2020Review
- Risk Factors of Pulmonary Complications After Minimally Invasive Surgery for Elderly Patients with Vertebral Compression Fractures.Therapeutics and clinical risk management · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The elderly population is rapidly growing and particularly diverse. Ageing leads to reduced organ function and a decline in physiologic reserve. Elderly patients are characterised by great inter-individual variability in physiological function with a high prevalence of chronic disease. In general, older patients have a higher risk of postoperative adverse outcomes, and frailty is a very important risk factor. This review article aims to provide a practical guide to anaesthetic management of the elderly surgical patient. To optimise care, clinicians should be familiar with the typical physiologic changes related to ageing and the implications for anaesthetic management. All anaesthetic techniques, methods and agents can be applied, if tailored to the patient's physiologic and pathologic changes. The elderly are more sensitive to anaesthetics, meaning that desired sedative and analgesic effects are reached at lower doses compared with younger patients, and the haemodynamic depressing side effects of anaesthetics are often more pronounced. To reduce the risk of circulatory collapse, the clinician should carefully titrate anaesthetics and await the response with patience. The dose of neuromuscular blocking agents should rarely be reduced for intubation, but the duration of action of neuromuscular blocking agents is often prolonged and difficult to predict. Perioperative neuromuscular monitoring is therefore strongly recommended. In the postoperative period, prevention of avoidable morbidity and functional decline is crucial; comprehensive multidisciplinary care and multimodal interventions may facilitate earlier recovery and decrease the risk of complications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.