Evidence map›Paper›PMID 27798763›Full record

ArticleJournal of the American Society for Mass Spectrometry2017

A High Voltage Power Supply That Mitigates Current Reversals in Capillary Zone Electrophoresis-Electrospray Mass Spectrometry.

Ryan J Flaherty, Scott A Sarver, Liangliang Sun, Greg A Brownell, David B Go, Norman J Dovichi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Evaluation of Prototype CE-MS Interfaces.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ryan J FlahertyDepartment of Chemistry, University of Notre Dame, Notre Dame, IN, 46556, USA.
Scott A SarverDepartment of Chemistry, University of Notre Dame, Notre Dame, IN, 46556, USA.
Liangliang SunDepartment of Chemistry, University of Notre Dame, Notre Dame, IN, 46556, USA.
Greg A BrownellDepartment of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA.
David B GoDepartment of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA.
Norman J DovichiDepartment of Chemistry, University of Notre Dame, Notre Dame, IN, 46556, USA. ndovichi@nd.edu.

Funding

Technology for single cell proteomics and its application to the analysis of single Xenopus blastomeresR01GM096767 · NIGMS · UNIVERSITY OF NOTRE DAME · PI DOVICHI, NORMAN J · 2011 to 2019
$2.5M
NIGMS NIH HHS R01 GM096767
6 · The paper itself

Abstract

Capillary electrophoresis coupled with electrospray ionization typically employs two power supplies, one at each end of the capillary. One power supply is located at the proximal (injection) end of the capillary. The power supply located at the distal (detector) end of the capillary drives the electrospray. Electrophoresis is driven by the difference in potential between these power supplies. Separations that employ large capillary inner diameter, high conductivity background electrolyte, and high separation potentials generate higher current than that produced by the electrospray. Excess current flows through the electrospray power supply. Most power supplies are not designed to sink current, and the excess current will cause the electrospray voltage to deviate from its set point. We report a simple circuit to handle this excess current, allowing separations under a wide range of electrophoretic conditions. Graphical Abstract ᅟ.

Indexed as

Capillary zone electrophoresisElectrospray power supply

Identifiers

PMID27798763
PMCPMC5233603

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.