Evidence map›Paper›PMID 27798733›Full record

Observational studyOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2017

A novel accelerometer-based method to describe day-to-day exposure to potentially osteogenic vertical impacts in older adults: findings from a multi-cohort study.

K Hannam, K C Deere, A Hartley, E M Clark, J Coulson, A Ireland, C Moss, M H Edwards, E Dennison, T Gaysin and 6 more

Registry-linked trialOpen access · hybridAbstract readObservational StudyValidation Study
In one paragraph

Observational study in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02984553 (The Use of Lactate Thresholds to Individualize Accelerometer Cut-points and Objectively Assess Physical Activity Levels in Postmenopausal Women), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02984553 unknown statusnot on this map

The Use of Lactate Thresholds to Individualize Accelerometer Cut-points and Objectively Assess Physical Activity Levels in Postmenopausal Women

TypeobservationalSponsorCentro de Estudios, Investigación y Medicina del DeporteRan2015 to 2017Enrolled80ConditionsPrimary Prevention
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Physical Activity Across Adulthood and Bone Health in Later Life: The 1946 British Birth Cohort.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019
    Trial
  3. Are associations between physical activity and bone mineral density in adults sex- and age-dependent? An analysis of the UK Biobank study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Effect of External Mechanical Stimuli on Human Bone: a narrative review.Progress in biomedical engineering (Bristol, England) · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Associations between physical activity and bone structure in older adults: does the use of self-reported versus objective assessments of physical activity influence the relationship?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Article
  13. Article
  14. The role of the microcirculation in muscle function and plasticity.Journal of muscle research and cell motility · 2019
    Review
  15. Day-to-day physical activity producing low gravitational impacts is associated with faster visual processing speed at age 69: cross-sectional study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2019
    Article
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

K HannamMusculoskeletal Research Unit, University of Bristol School of Clinical Sciences, Bristol, BS10 5NB, UK.
K C DeereMusculoskeletal Research Unit, University of Bristol School of Clinical Sciences, Bristol, BS10 5NB, UK.
A HartleyMusculoskeletal Research Unit, University of Bristol School of Clinical Sciences, Bristol, BS10 5NB, UK.
E M ClarkMusculoskeletal Research Unit, University of Bristol School of Clinical Sciences, Bristol, BS10 5NB, UK.
J CoulsonSchool of Healthcare Sciences, Manchester Metropolitan University, Manchester, M15 6BH, UK.
A IrelandSchool of Healthcare Sciences, Manchester Metropolitan University, Manchester, M15 6BH, UK.
C MossMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, SO16 6YD, UK.
M H EdwardsMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, SO16 6YD, UK.
E DennisonMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, SO16 6YD, UK.
T GaysinMRC Unit for Lifelong Health and Ageing at UCL, London, WC1E 6BT, UK.
R CooperMRC Unit for Lifelong Health and Ageing at UCL, London, WC1E 6BT, UK.
A WongMRC Unit for Lifelong Health and Ageing at UCL, London, WC1E 6BT, UK.
J S McPheeSchool of Healthcare Sciences, Manchester Metropolitan University, Manchester, M15 6BH, UK.
C CooperMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, SO16 6YD, UK.
D KuhMRC Unit for Lifelong Health and Ageing at UCL, London, WC1E 6BT, UK.
J H TobiasMusculoskeletal Research Unit, University of Bristol School of Clinical Sciences, Bristol, BS10 5NB, UK. Jon.Tobias@bristol.ac.uk.
University of Bristol · GBMRC Unit for Lifelong Health and Ageing · GBManchester Metropolitan University · GBUniversity of Southampton · GBUniversity College London · GB

Funding

Medical Research Council G0400491Medical Research Council MC_U147574212Medical Research Council MC_U147574234Medical Research Council MC_U147574237Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UU_12011/1Medical Research Council MC_UU_12019/4Medical Research Council MR/K024973/1Versus Arthritis 19583
6 · The paper itself

Abstract

This observational study assessed vertical impacts experienced in older adults as part of their day-to-day physical activity using accelerometry and questionnaire data. Population-based older adults experienced very limited high-impact activity. The accelerometry method utilised appeared to be valid based on comparisons between different cohorts and with self-reported activity.

introductionWe aimed to validate a novel method for evaluating day-to-day higher impact weight-bearing physical activity (PA) in older adults, thought to be important in protecting against osteoporosis, by comparing results between four cohorts varying in age and activity levels, and with self-reported PA levels.

methodsParticipants were from three population-based cohorts, MRC National Survey of Health and Development (NSHD), Hertfordshire Cohort Study (HCS) and Cohort for Skeletal Health in Bristol and Avon (COSHIBA), and the Master Athlete Cohort (MAC). Y-axis peaks (reflecting the vertical when an individual is upright) from a triaxial accelerometer (sampling frequency 50 Hz, range 0-16 g) worn at the waist for 7 days were classified as low (0.5-1.0 g), medium (1.0-1.5 g) or higher (≥1.5 g) impacts.

resultsThere were a median of 90, 41 and 39 higher impacts/week in NSHD (age 69.5), COSHIBA (age 76.8) and HCS (age 78.5) participants, respectively (total n = 1512). In contrast, MAC participants (age 68.5) had a median of 14,322 higher impacts/week. In the three population cohorts combined, based on comparison of beta coefficients, moderate-high-impact activities as assessed by PA questionnaire were suggestive of stronger association with higher impacts from accelerometers (0.25 [0.17, 0.34]), compared with medium (0.18 [0.09, 0.27]) and low impacts (0.13 [0.07,0.19]) (beta coefficient, with 95 % CI). Likewise in MAC, reported moderate-high-impact activities showed a stronger association with higher impacts (0.26 [0.14, 0.37]), compared with medium (0.14 [0.05, 0.22]) and low impacts (0.03 [-0.02, 0.08]).

conclusionsOur new accelerometer method appears to provide valid measures of higher vertical impacts in older adults. Results obtained from the three population-based cohorts indicate that older adults generally experience very limited higher impact weight-bearing PA.

Indexed as

AccelerometryAgedCohort StudiesExerciseFemaleGeriatric AssessmentHealth StatusHumansMaleOsteogenesisReproducibility of ResultsSelf ReportSocial ClassSurveys and QuestionnairesWalkingWeight-BearingAccelerometryBoneOlder adultsPhysical activity

Identifiers

PMID27798733
PMCPMC5306163
OpenAlexW2543901377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.