ArticleNature neuroscience2017
Vibrissa motor cortex activity suppresses contralateral whisking behavior.
Article in Nature neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 47 citations in OpenAlex.
- Decreased neural inhibitory state in fibromyalgia pain: A cross-sectional study.Neurophysiologie clinique = Clinical neurophysiology · 2020Trial
- Diversity in Whisking-Related Dynamics of Layer 5 Neurons in the Motor Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Multiple cortical systems influence a single vibrissa muscle.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Interchangeable Role of Motor Cortex and Reafference for the Stable Execution of an Orofacial Action.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Atavistic and vestigial anatomical structures in the head, neck, and spine: an overview.Anatomical science international · 2023Review
- Fast cortical dynamics encode tactile grating orientation during active touch.Science advances · 2021Article
- Cell Type-Specific Decrease of the Intrinsic Excitability of Motor Cortical Pyramidal Neurons in Parkinsonism.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Concurrent recordings of hippocampal neuronal spikes and prefrontal synaptic inputs from an awake rat.STAR protocols · 2021Article
- Body language signals for rodent social communication.Current opinion in neurobiology · 2021Review
- In Vivo Whole-Cell Patch-Clamp Methods: Recent Technical Progress and Future Perspectives.Sensors (Basel, Switzerland) · 2021Review
- Adaptive Whisking in Mice.Frontiers in systems neuroscience · 2021Article
- Functional Localization of an Attenuating Filter within Cortex for a Selective Detection Task in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Highly structured, partner-sex- and subject-sex-dependent cortical responses during social facial touch.Nature communications · 2019Article
- Opposing Influence of Sensory and Motor Cortical Input on Striatal Circuitry and Choice Behavior.Current biology : CB · 2019Article
- Resting State Networks in the TgF344-AD Rat Model of Alzheimer's Disease Are Altered From Early Stages.Frontiers in aging neuroscience · 2019Article
- More than Just a "Motor": Recent Surprises from the Frontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Review
- An Automated Water Task to Test Visual Discrimination Performance, Adaptive Strategies and Stereotyped Choices in Freely Moving Mice.Frontiers in behavioral neuroscience · 2018Article
- Neocortical dynamics during whisker-based sensory discrimination in head-restrained mice.Neuroscience · 2018Review
- Neural Representation of Motor Output, Context and Behavioral Adaptation in Rat Medial Prefrontal Cortex During Learned Behavior.Frontiers in neural circuits · 2018Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anatomical, stimulation and lesion data implicate vibrissa motor cortex in whisker motor control. Work on motor cortex has focused on movement generation, but correlations between vibrissa motor cortex activity and whisking are weak. The exact role of vibrissa motor cortex remains unknown. We recorded vibrissa motor cortex neurons during various forms of vibrissal touch, which were invariably associated with whisker protraction and movement. Free whisking, object palpation and social touch all resulted in decreased cortical activity. To understand this activity decrease, we performed juxtacellular recordings, nanostimulation and in vivo whole-cell recordings. Social touch resulted in decreased spiking activity, decreased cell excitability and membrane hyperpolarization. Activation of vibrissa motor cortex by intracortical microstimulation elicited whisker retraction, as if to abort vibrissal touch. Various vibrissa motor cortex inactivation protocols resulted in contralateral protraction and increased whisker movements. These data collectively point to movement suppression as a prime function of vibrissa motor cortex activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.