Evidence map›Paper›PMID 27798545›Full record

ArticleThe Pediatric infectious disease journal2017

Hospital-based Surveillance for Rotavirus Gastroenteritis Among Young Children in Bangladesh: Defining the Potential Impact of a Rotavirus Vaccine Program.

Syed M Satter, Paul A Gastanaduy, Khaleda Islam, Mahmudur Rahman, Mustafizur Rahman, Stephen P Luby, James D Heffelfinger, Umesh D Parashar, Emily S Gurley

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Article in The Pediatric infectious disease journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Syed M SatterFrom the *Programme for Emerging Infections, Infectious Diseases Division, International Centre for Diarrheal Disease Research (icddr,b), Dhaka, Bangladesh; †Division of Viral Diseases, Centers for Disease Control and Prevention(CDC), Atlanta, Georgia; ‡Department of Epidemiology, Institute of Epidemiology, Disease Control and Research (IEDCR), Dhaka, Bangladesh; §Center for Innovation in Global Health, Stanford University, Stanford, California; and ¶Western Pacific Regional Office, WHO, Manila, Philippines; Centers for Disease Control and Prevention(CDC), Atlanta, Georgia.
Paul A Gastanaduy
Khaleda Islam
Mahmudur Rahman
Mustafizur Rahman
Stephen P Luby
James D Heffelfinger
Umesh D Parashar
Emily S Gurley

Funding

CGH CDC HHS U51 GH001209World Health Organization 001
6 · The paper itself

Abstract

backgroundIn anticipation of introduction of a rotavirus vaccine into the national immunization program of Bangladesh, active hospital-based surveillance was initiated to provide prevaccine baseline data on rotavirus disease.

methodsChildren 5 years of age and younger admitted with acute gastroenteritis (AGE) (≥3 watery or looser-than-normal stools or ≥1 episode of forceful vomiting) at 7 hospitals throughout Bangladesh were identified. Clinical information and stool specimens were collected from every 4th patient. Specimens were tested for rotavirus antigen by enzyme immunoassays; 25% of detected rotaviruses were genotyped.

resultsFrom July 2012 to June 2015, rotavirus was detected in 2432 (64%) of 3783 children hospitalized for AGE. Eight enrolled children died, including 4 (50%) who were rotavirus positive. Rotavirus was detected year-round in Bangladesh with peak detection rates of >80% during November-February. Most (86%) rotavirus AGE cases were 6-23 months of age. Sixty-nine percent of children with rotavirus had severe disease (Vesikari score, ≥11). Among 543 strains genotyped, G1P[8] (31%) and G12P[8] (29%) were the most common.

conclusionsRotavirus is a major cause of morbidity in Bangladeshi children, accounting for nearly two-thirds of AGE hospitalizations. These data highlight the potential value of rotavirus vaccination in Bangladesh, and will be the key for future measurement of vaccine impact.

Indexed as

Public Health SurveillanceRotavirus VaccinesBangladeshChild, PreschoolCohort StudiesFemaleGastroenteritisHospitalizationHumansInfantInfant, NewbornMaleRotavirusRotavirus InfectionsVaccinationRotavirus Vaccines

Identifiers

PMID27798545
PMCPMC5242217

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.