ArticleNeurorehabilitation and neural repair2017
Associations Between Foot Placement Asymmetries and Metabolic Cost of Transport in Hemiparetic Gait.
Article in Neurorehabilitation and neural repair, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03916562 (Toward a Mechanistic Understanding of Optimization Principles Underlying Hemiparetic Gait), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Toward a Mechanistic Understanding of Optimization Principles Underlying Hemiparetic Gait
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effect of exercise on walking economy in patients with chronic neurological conditions: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Changes in interlimb coordination induced by within-stride changes in treadmill speed.Journal of neurophysiology · 2026Article
- Impact of unilateral knee restraint on symmetry adaptation and double-support phase dynamic stability during split-belt walking.Experimental brain research · 2025Article
- A biomechanics and energetics dataset of neurotypical adults walking with and without kinematic constraints.Scientific data · 2024Article
- Gait speed and individual characteristics are related to specific gait metrics in neurotypical adults.Scientific reports · 2023Article
- Speed-dependent biomechanical changes vary across individual gait metrics post-stroke relative to neurotypical adults.Journal of neuroengineering and rehabilitation · 2023Article
- Gait pattern after electromechanically-assisted gait training with the Hybrid Assistive Limb and conventional gait training in sub-acute stroke rehabilitation-A subsample from a randomized controlled trial.Frontiers in neurology · 2023Article
- Patterns of asymmetry and energy cost generated from predictive simulations of hemiparetic gait.PLoS computational biology · 2022Article
- Reduced joint motion supersedes asymmetry in explaining increased metabolic demand during walking with mechanical restriction.Journal of biomechanics · 2021Article
- Post-Stroke Adaptation of Lateral Foot Placement Coordination in Variable Environments.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2021Article
- Different Biomechanical Variables Explain Within-Subjects Versus Between-Subjects Variance in Step Length Asymmetry Post-Stroke.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2021Article
- Self-selected step length asymmetry is not explained by energy cost minimization in individuals with chronic stroke.Journal of neuroengineering and rehabilitation · 2020Article
- Musculoskeletal Model Personalization Affects Metabolic Cost Estimates for Walking.Frontiers in bioengineering and biotechnology · 2020Article
- Trading Symmetry for Energy Cost During Walking in Healthy Adults and Persons Poststroke.Neurorehabilitation and neural repair · 2019Article
- Autonomous Functional Movements in a Tendon-Driven Limb via Limited Experience.Nature machine intelligence · 2019Article
- Large Propulsion Demands Increase Locomotor Adaptation at the Expense of Step Length Symmetry.Frontiers in physiology · 2019Article
- Biomechanical mechanisms underlying exosuit-induced improvements in walking economy after stroke.The Journal of experimental biology · 2018Article
- Analysis of biases in dynamic margins of stability introduced by the use of simplified center of mass estimates during walking and turning.Gait & posture · 2018Article
- Neural Constraints Affect the Ability to Generate Hip Abduction Torques When Combined With Hip Extension or Ankle Plantarflexion in Chronic Hemiparetic Stroke.Frontiers in neurology · 2018Article
- Gait Asymmetry in People With Parkinson's Disease Is Linked to Reduced Integrity of Callosal Sensorimotor Regions.Frontiers in neurology · 2018Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Stroke survivors often have a slow, asymmetric walking pattern. They also walk with a higher metabolic cost than healthy, age-matched controls. It is often assumed that spatial-temporal asymmetries contribute to the increased metabolic cost of walking poststroke. However, elucidating this relationship is made challenging because of the interdependence between spatial-temporal asymmetries, walking speed, and metabolic cost. Here, we address these potential confounds by measuring speed-dependent changes in metabolic cost and implementing a recently developed approach to dissociate spatial versus temporal contributions to asymmetry in a sample of stroke survivors. We used expired gas analysis to compute the metabolic cost of transport (CoT) for each participant at 4 different walking speeds: self-selected speed, 80% and 120% of their self-selected speed, and their fastest comfortable speed. We also computed CoT for a sample of age- and gender-matched control participants who walked at the same speeds as their matched stroke survivor. Kinematic data were used to compute the magnitude of a number of variables characterizing spatial-temporal asymmetries. Across all speeds, stroke survivors had a higher CoT than controls. We also found that our sample of stroke survivors did not choose a self-selected speed that minimized CoT, contrary to typical observations in healthy controls. Multiple regression analyses revealed negative associations between speed and CoT and a positive association between asymmetries in foot placement relative to the trunk and CoT. These findings suggest that interventions designed to increase self-selected walking speed and reduce foot-placement asymmetries may be ideal for improving walking economy poststroke.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.