ArticlePhysiological reports2016
Simultaneous measurement of mitochondrial respiration and ATP production in tissue homogenates and calculation of effective P/O ratios.
Article in Physiological reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 37 citations in OpenAlex.
- Mitochondrial respiratory capacities are not linked to individual variation in hypoxia tolerance and standard metabolic rate in European seabass Dicentrarchus labrax.Journal of fish biology · 2026Article
- 3-Hydroxypropionic Acid Enhances Hair Growth-Related Signaling in Human Follicle Dermal Papilla Cells via Activation of the Wnt/β-Catenin Pathway.International journal of molecular sciences · 2026Article
- Ratiometric core/shell Nanosensors for Simultaneously Measuring Mitochondrial ATP Production and Oxygen Consumption in Living Cells.Phenomics (Cham, Switzerland) · 2025Article
- Evolutionary diversity of muscle OXPHOS efficiencyProceedings. Biological sciences · 2025Article
- The PACT Network: PRL, ARL, CNNM, and TRPM Proteins in Magnesium Transport and Disease.International journal of molecular sciences · 2025Review
- An evolving roadmap: using mitochondrial physiology to help guide conservation efforts.Conservation physiology · 2024Article
- The relationships between growth rate and mitochondrial metabolism varies over time.Scientific reports · 2022Article
- Links between host genetics, metabolism, gut microbiome and amoebic gill disease (AGD) in Atlantic salmon.Animal microbiome · 2022Article
- Cortisol Regulates Cerebral Mitochondrial Oxidative Phosphorylation and Morphology of the Brain in a Region-Specific Manner in the Ovine Fetus.Biomolecules · 2022Article
- Structural and biochemical evidence that ATP inhibits the cancer biomarker human aldehyde dehydrogenase 1A3.Communications biology · 2022Article
- Thermally tolerant intertidal triplefin fish (Tripterygiidae) sustain ATP dynamics better than subtidal species under acute heat stress.Scientific reports · 2021Article
- Targeting the Mild-Hypoxia Driving Force for Metabolic and Muscle Transcriptional Reprogramming of Gilthead Sea Bream (Biology · 2021Article
- Low oxygen levels can help to prevent the detrimental effect of acute warming on mitochondrial efficiency in fish.Biology letters · 2021Article
- Modulation of OSCP mitigates mitochondrial and synaptic deficits in a mouse model of Alzheimer's pathology.Neurobiology of aging · 2021Article
- Article
- Differences in mitochondrial efficiency explain individual variation in growth performance.Proceedings. Biological sciences · 2019Article
- Tissue-Specific Orchestration of Gilthead Sea Bream Resilience to Hypoxia and High Stocking Density.Frontiers in physiology · 2019Article
- Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost.Functional ecology · 2018Article
- Simultaneous measurement of mitochondrial respiration and ATP production in tissue homogenates and calculation of effective P/O ratios.Physiological reports · 2016Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of tissue homogenate has greatly aided the study of the functioning of mitochondria. However, the amount of ATP produced per oxygen molecule consumed, that is, the effective P/O ratio, has never been measured directly in tissue homogenate. Here we combine and refine existing methods previously used in permeabilized cells and isolated mitochondria to simultaneously measure mitochondrial ATP production (JATP) and oxygen consumption (JO
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.