Evidence map›Paper›PMID 27798156›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2016

Tissue Microenvironments in the Nasal Epithelium of Rainbow Trout (Oncorhynchus mykiss) Define Two Distinct CD8α+ Cell Populations and Establish Regional Immunity.

Ali Sepahi, Elisa Casadei, Luca Tacchi, Pilar Muñoz, Scott E LaPatra, Irene Salinas

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Mucosal immune response in biology, disease prevention and treatment.Signal transduction and targeted therapy · 2025
    Pooled it
  2. Article
  3. Article
  4. Understanding the Pathogenesis of Red Mark Syndrome in Rainbow Trout (Animals : an open access journal from MDPI · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Comparative models for human nasal infections and immunity.Developmental and comparative immunology · 2019
    Review
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ali SepahiCenter for Evolutionary and Theoretical Immunology, Department of Biology, University of New Mexico, Albuquerque, NM 87131.
Elisa CasadeiCenter for Evolutionary and Theoretical Immunology, Department of Biology, University of New Mexico, Albuquerque, NM 87131.
Luca TacchiCenter for Evolutionary and Theoretical Immunology, Department of Biology, University of New Mexico, Albuquerque, NM 87131.
Pilar MuñozDepartamento de Sanidad Animal, Facultad de Veterinaria, Campus de Excelencia Internacional Regional Campus Mare Nostrum, Universidad de Murcia, 30100 Murcia, Spain; and.
Scott E LaPatraClear Springs Foods Research Division, Buhl, ID 83316.
Irene SalinasCenter for Evolutionary and Theoretical Immunology, Department of Biology, University of New Mexico, Albuquerque, NM 87131; isalinas@unm.edu.
University of New Mexico · USTyson Foods (United States) · USUniversidad de Murcia · ES

Funding

Pilot Project ProgramP30GM110907 · NIGMS · UNIVERSITY OF NEW MEXICO · PI MILLER, ROBERT D · 2014 to 2018
$5.4M
COBRE Center for Evolutionary and Theoretical ImmunologyP20GM103452 · NIGMS · UNIVERSITY OF NEW MEXICO · PI LOKER, ERIC SAMUEL · 2012 to 2013
$4.2M
NIGMS NIH HHS P20 GM103452NIGMS NIH HHS P30 GM110907
6 · The paper itself

Abstract

Mucosal surfaces require balancing different physiological roles and immune functions. To effectively achieve multifunctionality, mucosal epithelia have evolved unique microenvironments that create unique regional immune responses without impairing other normal physiological functions. Whereas examples of regional immunity are known in other mucosal epithelia, to date, no immune microenvironments have been described in the nasal mucosa, a site where the complex functions of olfaction and immunity need to be orchestrated. In this study we identified the presence of CD8α

Indexed as

Immunity, CellularImmunity, MucosalAnimalsCD8 AntigensCD8-Positive T-LymphocytesCellular MicroenvironmentChemokine CCL19Fish ProteinsIntercellular Adhesion Molecule-1Nasal MucosaOncorhynchus mykissVascular Cell Adhesion Molecule-1CD8 antigen, alpha chainCD8 AntigensChemokine CCL19Fish ProteinsIntercellular Adhesion Molecule-1Vascular Cell Adhesion Molecule-1

Identifiers

PMID27798156
PMCPMC5123775
OpenAlexW2544703871

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.