Evidence map›Paper›PMID 27798119›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2017

Carrot solution culture bioproduction of uniformly labeled

Joshua W Smith, Randy B Rogers, Sookyoung Jeon, Stanislav S Rubakhin, Lin Wang, Jonathan V Sweedler, Martha Neuringer, Matthew J Kuchan, John W Erdman

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Nutrition research (New York, N.Y.) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Joshua W Smith1 Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Randy B Rogers2 Department of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Sookyoung Jeon1 Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Stanislav S Rubakhin3 Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Lin Wang3 Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Jonathan V Sweedler3 Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Martha Neuringer4 Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Matthew J Kuchan5 Abbott Nutrition, Columbus, OH 43219, USA.
John W Erdman1 Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
University of Illinois Urbana-Champaign · USAbbott Nutrition (United States)Oregon Health & Science University · US

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
NIH HHS P51 OD011092
6 · The paper itself

Abstract

Lutein is a xanthophyll abundant in nature and most commonly present in the human diet through consumption of leafy green vegetables. With zeaxanthin and meso-zeaxanthin, lutein is a component of the macular pigment of the retina, where it protects against photooxidation and age-related macular degeneration. Recent studies have suggested that lutein may positively impact cognition throughout the lifespan, but outside of the retina, the deposition, metabolism, and function(s) of lutein are poorly understood. Using a novel botanical cell culture system ( Daucus carota), the present study aimed to produce a stable isotope lutein tracer for use in future investigations of dietary lutein distribution and metabolism. Carrot cultivars were initiated into liquid solution culture, lutein production conditions optimized, and uniformly labeled

Indexed as

AnimalsCarbon IsotopesCells, CulturedChromatography, High Pressure LiquidDaucus carotaGlucoseHepatocytesLiverLuteinMacaca mulattaMass SpectrometryPlant ExtractsStaining and LabelingCarbon IsotopesGlucoseLuteinPlant Extractsisotopic tracerLuteinmass spectrometrynon-human primatenutritionphytochemicals

Identifiers

PMID27798119
PMCPMC5384503
OpenAlexW2537218016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.