Evidence map›Paper›PMID 27798024›Full record

Trial reportBMJ open2016

Rehabilitation Enablement in Chronic Heart Failure-a facilitated self-care rehabilitation intervention in patients with heart failure with preserved ejection fraction (REACH-HFpEF) and their caregivers: rationale and protocol for a single-centre pilot randomised controlled trial.

V Eyre, C C Lang, K Smith, K Jolly, R Davis, C Hayward, J Wingham, C Abraham, C Green, F C Warren and 11 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Pooled it
  3. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2019
    Pooled it
  4. Disease management interventions for heart failure.The Cochrane database of systematic reviews · 2019
    Pooled it
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 9 institutions in 1 country.

V EyrePeninsula Clinical Trials Unit, Plymouth University, Plymouth, UK.ORCID 0000-0003-0927-6815
C C LangSchool of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
K SmithSchool of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
K JollyInstitute for Applied Health Research, University of Birmingham, Birmingham, UK.
R DavisCardiology Department, Sandwell & West Birmingham Hospitals NHS Trust, Birmingham, UK.
C HaywardInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
J WinghamInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
C AbrahamPsychology Applied to Health Group, University of Exeter Medical School, Exeter, UK.
C GreenInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
F C WarrenInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
N BrittenInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
C J GreavesInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
P DohertyDepartment of Health Sciences, University of York, York, UK.
J AustinHeart Failure Services and Cardiac Rehabilitation, Aneurin Bevan University Health Board, Nevill Hall Hospital, Abergavenny, UK.
R Van LingenCardiology Department, Royal Cornwall Hospitals NHS Trust, Truro, UK.
S SinghCentre for Exercise and Rehabilitation Science, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK.
S BuckinghamInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
K PaulREACH-HF Patient and Public Involvement Group, c/o Research, Development & Innovation, Royal Cornwall Hospitals NHS Trust, Truro, UK.
R S TaylorInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
H M DalalInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
REACH-HF investigators
University of Exeter · GBRoyal Cornwall Hospital Trust · GBUniversity of Dundee · GBGlenfield Hospital · GBNevill Hall Hospital · GBSandwell & West Birmingham Hospitals NHS Trust · GBUniversity of Birmingham · GBUniversity of Plymouth · GBUniversity of York · GB

Funding

Department of Health RP-PG-1210-12004
6 · The paper itself

Abstract

introductionThe Rehabilitation EnAblement in CHronic Heart Failure in patients with Heart Failure (HF) with preserved ejection fraction (REACH-HFpEF) pilot trial is part of a research programme designed to develop and evaluate a facilitated, home-based, self-help rehabilitation intervention to improve self-care and quality of life (QoL) in heart failure patients and their caregivers. We will assess the feasibility of a definitive trial of the REACH-HF intervention in patients with HFpEF and their caregivers. The impact of the REACH-HF intervention on echocardiographic outcomes and bloodborne biomarkers will also be assessed. METHODS AND ANALYSIS: A single-centre parallel two-group randomised controlled trial (RCT) with 1:1 individual allocation to the REACH-HF intervention plus usual care (intervention) or usual care alone (control) in 50 HFpEF patients and their caregivers. The REACH-HF intervention comprises a REACH-HF manual with supplementary tools, delivered by trained facilitators over 12 weeks. A mixed methods approach will be used to assess estimation of recruitment and retention rates; fidelity of REACH-HF manual delivery; identification of barriers to participation and adherence to the intervention and study protocol; feasibility of data collection and outcome burden. We will assess the variance in study outcomes to inform a definitive study sample size and assess methods for the collection of resource use and intervention delivery cost data to develop the cost-effectiveness analyses framework for any future trial. Patient outcomes collected at baseline, 4 and 6 months include QoL, psychological well-being, exercise capacity, physical activity and HF-related hospitalisation. Caregiver outcomes will also be assessed, and a substudy will evaluate impact of the REACH-HF manual on resting global cardiovascular function and bloodborne biomarkers in HFpEF patients. ETHICS AND DISSEMINATION: The study is approved by the East of Scotland Research Ethics Service (Ref: 15/ES/0036). Findings will be disseminated via journals and presentations to clinicians, commissioners and service users. TRIAL REGISTRATION NUMBER: ISRCTN78539530; Pre-results .

Indexed as

ExerciseSelf CareStroke VolumeAdolescentAdultCaregiversChronic DiseaseFemaleHeart FailureHumansMalePilot ProjectsQuality of LifeResearch DesignCardiac RehabilitationCaregiversComplex InterventionPreserved Ejection FractionRandomised Controlled Trial

Identifiers

PMID27798024
PMCPMC5093626
OpenAlexW2543875784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.