Evidence map›Paper›PMID 27797893›Full record

ArticleClinical journal of the American Society of Nephrology : CJASN2017

Diet Soda Consumption and Risk of Incident End Stage Renal Disease.

Casey M Rebholz, Morgan E Grams, Lyn M Steffen, Deidra C Crews, Cheryl A M Anderson, Lydia A Bazzano, Josef Coresh, Lawrence J Appel

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical journal of the American Society of Nephrology : CJASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Prevalence of kidney disease of unknown etiology in agricultural workers, Guatemala.Revista panamericana de salud publica = Pan American journal of public health · 2023
    Article
  6. Review
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Casey M RebholzWelch Center for Prevention, Epidemiology, and Clinical Research, Baltimore, Maryland.
Morgan E GramsWelch Center for Prevention, Epidemiology, and Clinical Research, Baltimore, Maryland.
Lyn M SteffenDivision of Epidemiology & Community Health, University of Minnesota School of Public Health, Minneapolis, Minnesota.
Deidra C CrewsWelch Center for Prevention, Epidemiology, and Clinical Research, Baltimore, Maryland.
Cheryl A M AndersonDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Lydia A BazzanoDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.
Josef CoreshWelch Center for Prevention, Epidemiology, and Clinical Research, Baltimore, Maryland.
Lawrence J AppelWelch Center for Prevention, Epidemiology, and Clinical Research, Baltimore, Maryland.
Welch Foundation · USJohns Hopkins University · USTulane University · USUniversity of Minnesota · US

Funding

Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI POLLIN, TONI I. · 2005 to 2019
$17.3M
The comparative effectiveness of kidney transplantation in advanced CKDK08DK092287 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI GRAMS, MORGAN ERIKA · 2012 to 2016
$793k
Metabolomics for Identifying Biomarkers of Dietary Intake & Kidney Disease ProgressionK01DK107782 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI REBHOLZ, CASEY MARIE · 2016 to 2020
$778k
Race, Socioeconomic Status, Diet and Chronic Kidney DiseaseK23DK097184 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI CREWS, DEIDRA CANDICE · 2013 to 2016
$684k
NHLBI NIH HHS HHSN268201100005CNHLBI NIH HHS HHSN268201100005GNHLBI NIH HHS HHSN268201100005INHLBI NIH HHS HHSN268201100006CNHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201100007INHLBI NIH HHS HHSN268201100008CNHLBI NIH HHS HHSN268201100008INHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100009INHLBI NIH HHS HHSN268201100010CNHLBI NIH HHS HHSN268201100011CNHLBI NIH HHS HHSN268201100011INHLBI NIH HHS HHSN268201100012CNIDDK NIH HHS K01 DK107782NIDDK NIH HHS K08 DK092287NIDDK NIH HHS K23 DK097184NIDDK NIH HHS P30 DK072488
6 · The paper itself

Abstract

BACKGROUND AND

objectivesDiet soda consumption is common in the United States and is associated with impaired glucose metabolism, diabetes, and metabolic syndrome. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We prospectively analyzed diet soda consumption, assessed by food frequency questionnaire at baseline (1987-1989) and a follow-up examination (1993-1995), and incident ESRD through December 31, 2012 in the Atherosclerosis Risk in Communities study (n=15,368).

resultsBaseline mean age of participants was 54 years, 55% were female, and 27% were black. The majority of participants (43.5%) consumed <1 glass/wk of diet soda; 17.8% consumed 1-4 glasses/wk; 25.3% consumed 5-7 glasses/wk; and 13.5% consumed >7 glasses/wk. Over a median follow-up of 23 years, 357 incident ESRD cases were observed. Relative to <1 glass/wk of diet soda, consuming 1-4 glasses/wk, 5-7 glasses/wk, and >7 glasses/wk, respectively, was associated with 1.08-times (95% confidence interval [95% CI], 0.75 to 1.55), 1.33-times (95% CI, 1.01 to 1.75), and 1.83-times (95% CI, 1.01 to 2.52) higher risk of ESRD after adjusting for age, sex, race-center, education level, smoking status, physical activity, total caloric intake, eGFR, body mass index category, diabetes, systolic BP, and serum uric acid (P value for trend <0.001). Results were similar after additional adjustment for dietary acid load, diet quality, dietary sodium, dietary fructose, sugar-sweetened beverages, and dietary phosphorus. Risk estimates were similar by body mass index category (P value for interaction = 0.82), but the association between diet soda and ESRD was only significant for those who were overweight or obese at baseline. Sugar-sweetened beverage consumption was not significantly associated with ESRD in the fully adjusted model.

conclusionsDiet soda consumption was associated with higher ESRD risk in this general population sample. Further research is necessary to validate these findings in other study populations and to examine potential mechanisms through which diet soda could impact kidney disease.

Indexed as

Sweetening AgentsBeveragesBody Mass IndexDiet RecordsFemaleFollow-Up StudiesHumansIncidenceKidney Failure, ChronicMaleMiddle AgedObesityProspective StudiesRisk FactorsUnited StatesSweetening Agentsatherosclerosisbeveragesblood pressurebody mass indexdiabetes, mellitusdietenergy intakefemalefollow-up studiesfructoseglomerular filtration rateglucosekidney failure, chronicmetabolic syndrome Xmotor activityobesityoverweightphosphorus, dietarysmokingsodium, dietarysurveys and questionnairessweetening agentsUnited Statesuric acid

Identifiers

PMID27797893
PMCPMC5220651
OpenAlexW2544023822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.