Evidence map›Paper›PMID 27797005›Full record

ArticleProbiotics and antimicrobial proteins2016

Purification of Antibacterial CHAP

Elahe Seyed Hosseini, Rezvan Moniri, Yasaman Dasteh Goli, Hamed Haddad Kashani

Abstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  8. Article
  9. Evaluation of Cisplatin Efficacy on HepG2 and E. coli Cells under Acidic ConditionsAsian Pacific journal of cancer prevention : APJCP · 2019
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  10. Review
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  12. Selection of single-chain variable fragments specific forIranian journal of basic medical sciences · 2017
    Article
  13. Article
  14. Article
  15. Article
  16. A Novel Chimeric Endolysin with Antibacterial Activity against Methicillin-ResistantFrontiers in cellular and infection microbiology · 2017
    Article
  17. Production of Egg Yolk Antibody (IgY) AgainstAvicenna journal of medical biotechnology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Elahe Seyed HosseiniAnatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Rezvan MoniriAnatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Yasaman Dasteh GoliDepartment of Biology, University of Maryland, College Park, MD, 20742, USA.
Hamed Haddad KashaniAnatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran. hamedir2010@gmail.com.
Kashan University of Medical Sciences · IRUniversity of Maryland, College Park · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapeutic LysK-CHAP is a potent anti-staphylococcal protein that could be utilized as an antibiotic substitute. Intein-mediated protein purification is a reasonable and cost-effective method that is most recently used for recombinant therapeutic protein production. Intein (INT) is the internal parts of the protein that can be separated from the immature protein during protein splicing process. This sequence requires no specific enzyme or cofactor for separation. INT sequence and their characteristic of self-cleavage by thiol induction, temperature, and pH changes are used for protein purification. The current study presents the expression of CHAP

Indexed as

Anti-Bacterial AgentsEscherichia coliMethicillin-Resistant Staphylococcus aureusProtein DomainsRecombinant Fusion ProteinsAnti-Bacterial AgentsRecombinant Fusion ProteinsAntibacterial proteinCHAPK262 domainExpressionPurificationSelf-cleaving tagStaphylococcus aureus

Identifiers

PMID27797005
OpenAlexW2541934806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.