Evidence map›Paper›PMID 27796870›Full record

ArticleJournal of molecular neuroscience : MN2017

GPR30 Activation Contributes to the Puerarin-Mediated Neuroprotection in MPP

Yue-Fa Cheng, Guoqi Zhu, Qing-Wen Wu, Yue-Sheng Xie, Yan Jiang, Lan Guo, Ya-Li Guan, Ying-Shuo Liu, Jun Zhang

Abstract read
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In one paragraph

Article in Journal of molecular neuroscience : MN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yue-Fa ChengJitang College of North China University of Science and Technology, Tangshan, 063000, China. chengyuefa@hotmail.com.
Guoqi ZhuKey Laboratory of Xin'an Medicine, Ministry of Education, Anhui University of Chinese Medicine, Hefei, 230038, China.
Qing-Wen WuCollege of Nursing and Rehabilitation, North China University of Science and Technology, Tangshan, 063000, China.
Yue-Sheng XieJitang College of North China University of Science and Technology, Tangshan, 063000, China.
Yan JiangJitang College of North China University of Science and Technology, Tangshan, 063000, China.
Lan GuoJitang College of North China University of Science and Technology, Tangshan, 063000, China.
Ya-Li GuanJitang College of North China University of Science and Technology, Tangshan, 063000, China.
Ying-Shuo LiuJitang College of North China University of Science and Technology, Tangshan, 063000, China.
Jun ZhangJitang College of North China University of Science and Technology, Tangshan, 063000, China.
North China University of Science and Technology · CNAnhui University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neuroprotective action of puerarin in Parkinson's disease (PD) models has been well investigated. However, the mechanisms involved in protection have not been completely understood. G protein-coupled receptor 30 (GPR30) is a G protein-coupled estrogen receptor and considered a potential target in the neuroprotection against PD. In this study, we investigated whether puerarin prevented against 1-methyl-4-phenylpyridinium (MPP

Indexed as

1-Methyl-4-phenylpyridiniumCell DeathCell Line, TumorGlial Cell Line-Derived Neurotrophic FactorHumansIsoflavonesNeuronsNeuroprotective AgentsReceptors, EstrogenReceptors, G-Protein-Coupled1-Methyl-4-phenylpyridiniumGlial Cell Line-Derived Neurotrophic FactorGPER1 protein, humanIsoflavonesNeuroprotective AgentspuerarinReceptors, EstrogenReceptors, G-Protein-CoupledGPR30mTorNew protein synthesisParkinson’s diseasePuerarin

Identifiers

PMID27796870
OpenAlexW2541101275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.