ReviewCurrent cardiology reports2016
Recent Advances in Leukoaraiosis: White Matter Structural Integrity and Functional Outcomes after Acute Ischemic Stroke.
Review in Current cardiology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 50 citations in OpenAlex.
- White Matter Microstructural Injury in Patients With Acute Single Subcortical Infarction: A Preliminary Tract-Based Spatial Statistics With Atlas-Based Analysis.Neural plasticity · 2026Article
- Damage to white matter networks resulting from small vessel disease and the effects on cognitive function.Scientific reports · 2025Article
- Orchestrating the frontline: HDAC3-miKO recruits macrophage reinforcements for accelerated myelin debris clearance after stroke.Theranostics · 2025Article
- Advanced brain aging mediates the relationship between cardiovascular health and aphasia severity in chronic stroke.Aging brain · 2025Article
- Treatment of Shengqingtongqiao Decoction for mild cognitive impairment of white matter lesions study protocol for a randomized, double-blind, double-dummy, parallel controlled trial.BMC complementary medicine and therapies · 2024Article
- Usefulness of automated tractography for outcome prediction in patients with recurrent stroke.Journal of physical therapy science · 2024Article
- Regional brain aging: premature aging of the domain general system predicts aphasia severity.Communications biology · 2024Article
- Association of coagulation markers with the severity of white matter hyperintensities in cerebral small vessel disease.Frontiers in neurology · 2024Article
- Neuroimaging markers of patient-reported outcome measures in acute ischemic stroke.medRxiv : the preprint server for health sciences · 2023Article
- White matter hyperintensity load mediates the relationship between age and cognition.Neurobiology of aging · 2023Article
- Longitudinal Progression of White Matter Hyperintensity Severity in Chronic Stroke Aphasia.Archives of rehabilitation research and clinical translation · 2023Article
- Lower socioeconomic status is associated with premature brain aging.Neurobiology of aging · 2023Article
- Advanced Brain Age and Chronic Poststroke Aphasia Severity.Neurology · 2023Article
- Moderate-Severe White Matter Lesion Predicts Delayed Intraventricular Hemorrhage in Intracerebral Hemorrhage.Neurocritical care · 2022Article
- Article
- Association of Vascular Properties With the Brain White Matter Hyperintensity in Middle-Aged Population.Journal of the American Heart Association · 2022Article
- Influence of cerebral microbleeds on mechanical thrombectomy outcomes.Scientific reports · 2022Article
- Brain age predicts long-term recovery in post-stroke aphasia.Brain communications · 2022Article
- Observational
- Pathogenesis and research progress in leukoaraiosis.Frontiers in human neuroscience · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Leukoaraiosis, a radiographic marker of cerebral small vessel disease detected on T2-weighted brain magnetic resonance imaging (MRI) as white matter hyperintensity (WMH), is a key contributor to the risk and severity of acute cerebral ischemia. Prior investigations have emphasized the pathophysiology of WMH development and progression; however, more recently, an association between WMH burden and functional outcomes after stroke has emerged. There is growing evidence that WMH represents macroscopic injury to the white matter and that the extent of WMH burden on MRI influences functional recovery in multiple domains following acute ischemic stroke (AIS). In this review, we discuss the current understanding of WMH pathogenesis and its impact on AIS and functional recovery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.