Evidence map›Paper›PMID 27796579›Full record

ArticlePflugers Archiv : European journal of physiology2016

Calcium is not required for triggering volume restoration in hypotonically challenged A549 epithelial cells.

Olga Ponomarchuk, Francis Boudreault, Sergei N Orlov, Ryszard Grygorczyk

Abstract read
PubMed Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Wide field of view quantitative imaging of cellular ATP release.American journal of physiology. Cell physiology · 2019
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Olga PonomarchukCentre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM), Tour Viger 900 rue St-Denis, Montreal, Quebec, H2X 0A9, Canada.
Francis BoudreaultCentre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM), Tour Viger 900 rue St-Denis, Montreal, Quebec, H2X 0A9, Canada. francis.boudreault.crchum@gmail.com.
Sergei N OrlovFaculty of Biology, M.V. Lomonosov Moscow State University, Moscow, Russia.
Ryszard GrygorczykCentre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM), Tour Viger 900 rue St-Denis, Montreal, Quebec, H2X 0A9, Canada. ryszard.grygorczyk@umontreal.ca.ORCID 0000-0002-9798-7651
Centre Hospitalier de l’Université de Montréal · CALomonosov Moscow State University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maintenance of cell volume is a fundamental housekeeping function in eukaryotic cells. Acute cell swelling activates a regulatory volume decrease (RVD) process with poorly defined volume sensing and intermediate signaling mechanisms. Here, we analyzed the putative role of Ca

Indexed as

Cell SizeOsmotic PressureAction PotentialsCalciumCalcium ChannelsCalcium SignalingCell Line, TumorEpithelial CellsHumansCalciumCalcium ChannelsCalcium signalingOsmotic shockRegulatory volume decreaseVRAC

Identifiers

PMID27796579
OpenAlexW2543946168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.