Evidence map›Paper›PMID 27796552›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2017

A comparison of clinicopathological features and surgical outcomes between pediatric skull base and non-skull base meningiomas.

Zhicen Li, Hao Li, Yuming Jiao, Ji Ma, Shuo Wang, Jizong Zhao, Yong Cao

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Clinical features and long-term outcomes of pediatric meningiomas.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhicen LiDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Beijing, 100050, China.
Hao LiDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Beijing, 100050, China.
Yuming JiaoDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Beijing, 100050, China.
Ji MaDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Beijing, 100050, China.
Shuo WangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Beijing, 100050, China.
Jizong ZhaoDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Beijing, 100050, China.
Yong CaoDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Beijing, 100050, China. caoyong6@hotmail.com.
Beijing Tian Tan Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectThe purpose of this study is to analyze and compare the clinicopathological characteristics and surgical outcomes between skull base and non-skull base meningiomas in pediatric population.

methodsWe retrospectively analyzed a total of 140 cases of pediatric meningiomas surgically treated in our department from January 2005 to July 2015 and compared the clinicopathological characteristics and surgical outcomes between skull base and non-skull base meningiomas.

resultsOf all the pediatric meningiomas, 50 (35.8 %) were located at the skull base and 90 (64.2 %) were located at the non-skull base. Skull base and non-skull base meningiomas had a similar sex distribution (male/female = 1:1 in skull base meningiomas and male/female = 1.5:1 in non-skull base meningiomas) (P = 0.288) and high-grade meningioma occurrence rate (P = 0.569). In addition, the mean age of non-skull base meningiomas was 12.5 years which was younger than that of skull base meningiomas (14.2 years) (P = 0.019), and the preoperative tumor size was smaller in skull base (mean size = 4.7 cm in skull base meningiomas and mean size = 5.7 cm in non-skull base meningiomas) (P = 0.020). Gross total resection was achieved in 64 non-skull base patients (73.9 %) and 26 skull base patients (52 %) (P = 0.046). Patients with gross total resection had better progression free survival (PFS) than those with subtotal resection.

conclusionPediatric skull base and non-skull base meningiomas are similar in sex distribution and high-grade meningioma occurrence rate. In comparison with non-skull base ones, pediatric skull base meningiomas occur at elder age and are smaller in size and they are more likely to be incompletely resected. Gross total resection and early treatment are recommended to prolong PFS of pediatric patients.

Indexed as

Treatment OutcomeAdolescentChildChild, PreschoolDisease-Free SurvivalFemaleHumansInfantLongitudinal StudiesMaleMeningeal NeoplasmsMeningiomaNeurosurgical ProceduresRegression AnalysisRetrospective StudiesSkull BaseClinical featuresOutcomesPediatric meningiomasSkull base

Identifiers

PMID27796552
OpenAlexW2540458738

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.