Evidence map›Paper›PMID 27796543›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2017

Thoracic aorta calcification but not inflammation is associated with increased cardiovascular disease risk: results of the CAMONA study.

Björn A Blomberg, Pim A de Jong, Anders Thomassen, Marnix G E Lam, Werner Vach, Michael H Olsen, Willem P T M Mali, Jagat Narula, Abass Alavi, Poul F Høilund-Carlsen

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 120 citations in OpenAlex.

  1. Sodium fluoride in cardiovascular disorders: A systematic review.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Pooled it
  2. Vascular uptake onJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Trial
  3. European journal of nuclear medicine and molecular imaging · 2020
    Trial
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  6. Spinal cord FDG PET uptake in healthy adults: an AI-driven segmentation study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
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  8. American journal of nuclear medicine and molecular imaging · 2026
    Article
  9. Preclinical evaluation of high-resolution CT,European journal of nuclear medicine and molecular imaging · 2025
    Article
  10. Observational
  11. Reproducibility ofCurrent cardiology reports · 2025
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  12. Article
  13. Review
  14. American journal of nuclear medicine and molecular imaging · 2025
    Article
  15. Article
  16. Quantitative aortic Na[European journal of nuclear medicine and molecular imaging · 2025
    Article
  17. Article
  18. Invasive electrochemical impedance spectroscopy with phase delay for experimental atherosclerosis phenotyping.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  19. Correlation ofArchives of endocrinology and metabolism · 2024
    Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Björn A BlombergDepartment of Nuclear Medicine, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense C, Denmark. b.a.blomberg@umcutrecht.nl.
Pim A de JongDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Anders ThomassenDepartment of Nuclear Medicine, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense C, Denmark.
Marnix G E LamDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Werner VachClinical Epidemiology, Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Freiburg, Germany.
Michael H OlsenThe Cardiovascular and Metabolic Preventive Clinic, Department of Endocrinology, Center for Individualized Medicine in Arterial Diseases, Odense University Hospital, Odense, Denmark.
Willem P T M MaliDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Jagat NarulaIcahn School of Medicine, Mount Sinai Hospital, New York, NY, USA.
Abass AlaviDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Poul F Høilund-CarlsenDepartment of Nuclear Medicine, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense C, Denmark.
University Medical Center Utrecht · NLOdense University Hospital · DKHospital of the University of Pennsylvania · USMount Sinai Hospital · USUniversity Medical Center Freiburg · DEUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeArterial inflammation and vascular calcification are regarded as early prognostic markers of cardiovascular disease (CVD). In this study we investigated the relationship between CVD risk and arterial inflammation (

methodsStudy participants underwent blood pressure measurements, blood analyses, and

resultsA total of 139 subjects (52 % men, mean age 49 years, age range 21 - 75 years, median FRS 6 %) were evaluated. CVD risk was, on average, 3.7 times higher among subjects with thoracic aorta Na

conclusionOur findings indicate that an unfavourable CVD risk profile is associated with marked increases in vascular calcification metabolism and vascular calcium burden of the thoracic aorta, but not with arterial inflammation.

Indexed as

Fluorodeoxyglucose F18Sodium FluorideAdultAgedAorta, ThoracicAortitisAtherosclerosisCausalityComorbidityDenmarkHumansLongitudinal StudiesMaleMiddle AgedPositron Emission Tomography Computed TomographyPrevalenceFluorodeoxyglucose F18RadiopharmaceuticalsSodium Fluoride[18F]Fluorodeoxyglucose (18F-FDG)[18F]Sodium fluoride (Na18F)Arterial inflammationAtherosclerosisPET/CTVascular calcification

Identifiers

PMID27796543
PMCPMC5214929
OpenAlexW2544521075

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.