SynthesisRheumatology international2017
Prevalence and factors associated with disturbed sleep in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review.
Synthesis in Rheumatology international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Prevalence of sleep disturbance in patients with ankylosing spondylitis: a systematic review and meta-analysis.Advances in rheumatology (London, England) · 2023Pooled it
- Experiences of group-based cognitive behavioural therapy for insomnia among patients with rheumatoid arthritis: a qualitative study.BMJ open · 2023Trial
- High-Intensity Exercise Improves Fatigue, Sleep, and Mood in Patients With Axial Spondyloarthritis: Secondary Analysis of a Randomized Controlled Trial.Physical therapy · 2020Trial
- Evidence on physical activity-sleep associations in axial spondyloarthritis: a scoping review of current findings.Rheumatology international · 2026Article
- Sleep disorders in RA, axSpA and PsA are common despite good disease activity control-direct comparison of sleep quality and its risk factors using MDHAQ and PSQI.Clinical rheumatology · 2026Article
- Restless legs syndrome and hashimoto's thyroiditis.Acta neurologica Belgica · 2026Article
- Study of Sleep Problem in Rheumatoid Arthritis and Its Impact on Disease Activity, Pain Perception, and Functional Disability.Annals of African medicine · 2025Article
- Sleep disorders in rheumatoid arthritis, axial spondyloarthritis and psoriatic arthritis.Rheumatology international · 2025Review
- Analysis of sleep disorders and their influencing factors in patients with ankylosing spondylitis.PloS one · 2025Article
- Anxiety and depression as potential risk factors for limited pain management in patients with elderly knee osteoarthritis: a cross-lagged study.BMC musculoskeletal disorders · 2024Article
- Effects of serum inflammatory factors, health index and disease activity scores on ankylosing spondylitis patients with sleep disorder.World journal of psychiatry · 2024Article
- Risk of motor vehicle accidents with profound injuries in patients with ankylosing spondylitis: a nationwide, population-based cohort study.Therapeutic advances in musculoskeletal disease · 2024Article
- The Taiwanese Map of Axial Spondyloarthritis: Living with the Condition.Medicina (Kaunas, Lithuania) · 2023Article
- Is Restless Legs Syndrome De Facto Thyroid Disease?Biomedicines · 2022Article
- Development of a screening tool to identify patients with axial spondyloarthritis: a cognitive interview study.Clinical rheumatology · 2022Article
- Factors associated with the inflammatory process in pain in ankylosing spondylitis.The Pan African medical journal · 2022Article
- Anxiety and depression among patients with axial spondyloarthritis.European journal of rheumatology · 2022Article
- Ixekizumab improves sleep and work productivity in patients with non-radiographic axial spondyloarthritis: results from the COAST-X trial at 52 weeks.BMC rheumatology · 2021Article
- Bath Ankylosing Spondylitis Disease Activity Index is Associated With the Quality of Sleep in Ankylosing Spondylitis Patients.Journal of rheumatic diseases · 2021Article
- Rapid improvement in spinal pain in patients with axial spondyloarthritis treated with secukinumab: primary results from a randomized controlled phase-IIIb trial.Therapeutic advances in musculoskeletal disease · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review explores the prevalence and factors associated with disturbed sleep for patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis in order to clarify consistent findings in this otherwise disparate research field. The association of physical, demographic and psychological factors correlating with poor sleep was explored, and the effectiveness of interventions assessed. Ten electronic databases were searched: AMED, CINAHL, Embase, Medline, PsycINFO, PubMed, Scopus, Web of Science, OpenGrey and BASE. Following application of inclusion and exclusion criteria, 29 articles were critically assessed on the basis of methodology, experimental design, ethics and quality of sleep data, leading to the selection of 15 studies for final review. Poor sleep was reported in 35-90% of patients with axial spondyloarthritis and is more prevalent within this clinical population compared to healthy control subjects. Disturbed sleep is an important aspect of disease for patients and reflects the severity of disease activity, pain, fatigue and functional disability. However, the direction of this relationship is undetermined. Associations with age, gender, years spent in education, quality of life and depression have also been demonstrated. Anti-TNF medication is effective in reducing poor sleep, and exercise has also produced beneficial results. Future research into poor sleep should take account of its multifactorial nature. There is also a current lack of research investigating non-pharmacological interventions or combination therapies. A standardised, validated measurement of poor sleep, appropriate for regular patient screening, would be a useful first step for future research.
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